Remote Longitudinal Follow-up of Participants in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: To assess a personalized protocol focused on maintaining contact for long-term follow-up of current and former clinical research participants Background: PPMI-FOUND enrolls participants at…Endogenous reproductive factors and risk of Parkinson’s disease in women: a systematic review and meta-analysis of observational studies
Objective: To provide an updated synthesis of existing evidence and critically appraise previous methodological approaches, we conducted a systematic review and meta-analysis of observational studies…Clinical and Patient-Reported Outcomes in Patients With and Without Severe Bradykinesia According to Sensor Measurements
Objective: To explore clinical and patient-reported outcomes in patients with and without severe sensor-measured bradykinesia in patients with Parkinson’s disease (PD). Background: Parkinson's disease (PD)…Non‑Motor Outcomes after STN-FUS for Parkinson’s disease
Objective: To assess changes in non-motor symptoms(NMS) in PD after focused ultrasound subthalamotomy(STN-FUS). Background: NMS impair quality of life in PD.STN-FUS improves motor signs in PD but…Neurofilament Light Chain Triggers Protein Aggregation, Neurotoxicity and Gliosis in Parkinson’s Disease through p38/MK2/NF-κB/CREB1 and Nrf2/HO-1 Signalling
Objective: This research investigated the active pathogenic property of Neurofilament light chain (NfL) in contributing to PD-like pathophysiology. We aimed to elucidate these mechanisms by…Functional Belly Dancer Dyskinesia Associated with Abdominal Pain: A Case Series
Objective: To describe belly dancer dyskinesia (BDD) presenting as a manifestation of functional movement disorder associated with abdominal pain, and to emphasize the role of…Genetic Predictors in Dystonia: A Phenotypic Analysis.
Objective: To identify clinical predictors of genetic positivity in dystonia and to develop a phenotype-based predictive score to guide genetic testing. Background: Dystonia is a…Home-based cerebellar transcranial stimulation for multiple system atrophy: A randomized trial
Objective: To evaluate whether home-based, remotely supervised cerebellar transcranial direct current stimulation (tDCS) can improve motor, cognitive and affective symptoms in patients with the cerebellar…Altered Glia Limitans Structure and Function in Parkinson’s Disease and Multiple System Atrophy
Objective: To investigate functional alterations of the glia limitans and the consequent changes in glymphatic system dynamics and CD4⁺ T cell infiltration in the disease-affected…PDGFB Mutations may Induce Primary Brain Calcification via the Gain-of-Function Mechanism
Objective: This study aims to investigate the expression level of reported PDGFB mutations in human cerebral microvascular endothelial cells (hCMEC/D3), and further propose a potential…
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