Drug-Induced Movement Disorders in Elderly Patients with Dementia: A Case Study of Acute Dystonia Following Third-Generation Antipsychotic Use
Objective: To represent a case of acute dystonic dyskinesias after breхpiprazole use by the patient with frontotemporal dementia (behavioral variant) Background: Drug-induced movement disorders (DIMDs)…A Mixed Reality Multimodal System for Objective Assessment of Motor and Cognitive Functions in Neurodegenerative Diseases
Objective: This study aimed to develop an immersive system using Microsoft HoloLens 2 for assessing motor and cognitive functions by integrating speech, movement, and eye-tracking…Efficacy and Feasibility of Telemedicine-Based Dietary Intervention vs. Outpatient Supervision for Drug-Resistant Multiple System Atrophy in Postmenopausal Women During COVID-19
Objective: This study aimed to evaluate the feasibility, safety, and patient satisfaction of initiating and following up on MAD via telemedicine using the Telegram app,…The Phenomena of “Meryacheniye” and “Kliukushestvo” in Yakutia in the 20th Century
Objective: To review the characteristics of psychogenic movement disorders in Yakutia. Background: At the beginning of the 20th century, the conditions known as “meryacheniye” and…Spastic Paraplegia as a Novel Phenotype in Late Adulthood Onset POLG Disease: A Pathophysiological Continuum?
Objective: We report a case of late adult onset gradually progressive spastic paraplegia secondary to pathogenic variants in the POLG gene. Background: Many pathogenic mutations…Uncommon Presentation of Moyamoya Disease (MMD): A Case of Negative Myoclonus
Objective: We describe a case of MMD in which the patient presented with negative myoclonus. Background: Moyamoya disease (MMD) is a progressive cerebrovascular disorder characterized…The Potential Long-Term Economic Impact of Continuous Monitoring in Parkinson’s Disease
Objective: The economic burden of Parkinson's disease (PD) is influenced by the time patients spend in OFF state, when medication efficacy declines, and symptoms worsen.…Amitriptyline-Induced Rabbit Syndrome: A Case of Refractory Oral Vertical Dyskinesia
Objective: We present a case of refractory rabbit syndrome associated with the use of amitriptyline, a tricyclic antidepressant, highlighting both the diagnostic and therapeutic challenges…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…Deep Learning-Driven Discovery of Mitochondrial Genomic Instability in Parkinson’s Disease: A Single-Cell Multi-Omics Approach
Objective: This study integrates snRNA-seq and proteomic data to (i) map mtDNA heteroplasmic mutations at single-cell resolution, (ii) identify mitochondrial-driven transcriptional dysregulation, and (iii) classify…
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