Targeted Brain Delivery of Rifampicin via PEG-PLA Nanoparticles: A Promising Therapeutic Strategy for Neuroprotection and Disease Modification in Parkinsonian Mouse Models
Objective: This study aimed to design and validate a nanoparticle-based delivery system for rifampicin, with the objective of enhancing its therapeutic efficacy, improving brain targeting,…Comparative Analysis of Trunk Sensor Placement for Movement Data Collection in the OxQUIP Study
Objective: This study aims to evaluate the accuracy of balance and walking kinematic data derived from a smartphone placed on the abdomen, compared to a…Language influence on acoustic measures of sustained vowel in patients with Parkinson’s disease and healthy volunteers
Objective: To investigate the influence of language on acoustic measures of sustained vowels in patients with Parkinson’s disease and healthy volunteers, specifically focusing on jitter,…Embodying a Sixth Soft Finger. How Wearing a Supernumerary Robotic Digit Impacts our Body Schema
Objective: To assess whether a supernumerary robotic digit can enter into the user’s body schema, thereby altering bodily self-representation and proprioceptive awareness. Background: Stroke is…A Mixed Reality Multimodal System for Objective Assessment of Motor and Cognitive Functions in Neurodegenerative Diseases
Objective: This study aimed to develop an immersive system using Microsoft HoloLens 2 for assessing motor and cognitive functions by integrating speech, movement, and eye-tracking…Efficacy and Feasibility of Telemedicine-Based Dietary Intervention vs. Outpatient Supervision for Drug-Resistant Multiple System Atrophy in Postmenopausal Women During COVID-19
Objective: This study aimed to evaluate the feasibility, safety, and patient satisfaction of initiating and following up on MAD via telemedicine using the Telegram app,…Transcranial Magnetic Stimulation as Treatment for Functional Movement Disorders: Experiences from a Single Centre Retrospective Audit
Objective: St Vincent’s Hospital Sydney has been offering Transcranial Magnetic Stimulation (TMS) to adult patients with a diagnosis of Functional Movement Disorders (FMD) since 2020.…Oculopalatal Myoclonus Secondary to Brainstem Hemorrhage: A Case Report
Objective: To present a case of oculopalatal myoclonus (OPM) secondary to brainstem hemorrhage. Background: OPM is an acquired syndrome characterized by synchronized pendular nystagmus with…MDS Task Force on Tic Disorders: Development of a New Classification Scheme for Tic Disorders
Objective: To establish a clear definition and axis classification scheme for tics that serves to separate phenomenology from etiology. Background: Gilles de la Tourette documented…IPX203 (ER CD-LD) super-responders: Description of a patient subpopulation reaping extra benefits in dose-response when converting from IR CD-LD
Objective: To generate quantitative data helping dose optimization when converting Parkinson’s disease (PD) patients from IR CD-LD to IPX203. Background: IPX203 is the first extended-release…
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