Objective: To study the features of the flow of parkinsonism with congenital anomalies of cerebral vessels.

Background: Analysis of the study of neurological status, data of multispiral computed tomography (MSCT) with angiography, with in the diagnosis of congenital anomalies of cerebral vessels.

Method: 40 patients with abnormalities of cerebral vessels (25 women and 15 men) aged 42–57 years (mean age 45 ± 2.2 years) were under our observation.

Results: Angiodysplasias were found in all the examined 100%. Cerebral symptoms in the form of headaches- (100%), dizziness- (86%), postural instability- (65%), and in 45% of cases for a long time before the onset of the first symptoms of the disease impaired sense of smell, disturbed sleep, 37.7% increased sweating-23.9%. In neurostatus, 95% of cases prevailed, stiffness and puppet walk, amymia, 45% lack of physiological synkinesis, 37.1% resting tremor, diffuse neurological symptoms. Analysis of data from multispiral computed tomography with angiography showed the presence of changes in 100% of cases. Moreover, pathological tortuosities in videgipoplasia, the absence of key elements of the Wils circle, kingking and coiling were more common in women, 53% than in men, 47% and more in the internal carotid artery, 72.3%, 7%. In the group of patients with changes in the vertebral arteries, structural changes in the cervical spine were found. In addition, in a survey of 47.3% of patients, the vertebral artery hypoplasia, 25.5% of the middle cerebral artery and in 13.5% of the posterior connective artery were detected, indicating a hereditary etiology of angiodysplasias.

Conclusion: Angiodysplasia of cerebral vessels can be a risk factor for the development of parkinsonism.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/special-features-of-parkinsonism-with-congenital-anomalies-of-cerebral-vessels/