Objective: We present a wearable inertial system for the evaluation of motor symptoms in Parkinson’s Disease.

Background: PD is the second neurodegenerative disease affecting to around 10 million people around the world and some studies are claiming that this number will double by 2040. Parkinson’s Disease (PD) is characterized by a big number of motor symptoms that severely affects the function of a person and that usually, are difficult to assess in current clinical practice. The use of inertial systems in the field of health has meant a great advance in the enhancement of quality of life of people with some health problem and, more concretely, in the field of Parkinson’s Disease (PD). Current evaluations are based on questionnaires or specific tests at the doctor’s office, where the patient does not show the real symptoms suffered at their homes. Other methods are diaries, but they have reduced compliance and recall bias.

Method: STAT-ON® is a certified medical device capable to detect PD motor symptoms through the execution of real-time embedded algorithms. This is a wearable device that works as a Holter, enabling a long-term monitoring of the patient in patient’s natural environments. All the algorithms have been trained in a database with 92 patients with PD, being, as far as authors know, the largest inertial database with PD patients. The embedded algorithms detect: ON/OFF states, bradykinetic gait, dyskinesia, freezing of gait, gait parameters and quantity of movement.

Results: In the field of Parkinson’s Disease, STAT-ON® presents results of geometric mean between sensitivity and specificity in bradykinesia of 0.84, 0.94 in dyskinesia, 0.85 in freezing of gait and 0.93 in ON-OFF detection. A total of 143 patients have participated in validation studies such as UPDRS correlation and diaries vs sensor outcomes comparison.

Conclusion: The STAT-ON® system is capable to objectively evaluate the motor state of a patient in his/her daily life activities acting as a Holter.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/stat-on-a-wearable-inertial-system-to-objectively-evaluate-motor-symptoms-in-parkinsons-disease/