Session Information
Date: Tuesday, June 21, 2016
Session Title: Technology
Session Time: 12:30pm-2:00pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: To test feasibility and utility of home-based video-recording uploaded from a mobile device app to a cloud-based storage platform, in order to quantitate motor signs in patients with Parkinson’s disease (PD).
Background: The requirement for face-to-face evaluation of patients when administering the Unified Parkinson’s disease Rating Scale (UPDRS) limits ability to collect patient data due to logistical issues including mobility, travel, and time. What is needed is a simple, reliable, and secure means of remotely collecting clinical and clinical research data.
Methods: Sixteen participants with PD were trained to record a self-administered 11 item short version UPDRS (svUPDRS) using an iPod touch™ device. In-office recordings were made at baseline and week 4 for comparison with in-person UPDRS rating, and patients uploaded 3 interim weekly home recordings of the svUPDRS to a HIPAA-compliant cloud-based platform using CaptureProof™ technology.
Results: Mean age of participants was 67 ± 8 years; there were 9 men and 7 women; mean education was 18 ± 2 years; and 13/16 reported daily smart phone use. Mean PD duration was 6.4 ± 2.8 years; mean UPDRS Part III in the “on” state was 25 ± 9.7 points. Fourteen of the 16 participants had 100% compliance with scheduled home recording activities, and successfully recorded and uploaded 98% of the modules at the 3 pre-specified weekly intervals. One participant withdrew due to illness, and 1 completed only the baseline visit. One participant required retraining, but was subsequently able to complete the study. Pearson Correlation Coefficient at visits 1 and 4 for recorded svUPDRS versus equivalent items from the in-person in-office ratings was 0.68 (p=0.008). Participants reported both technological and logistical barriers to home video-recording including difficulty using the iPod touch small screen, and the need for a partner for iPod touch™ recording.
Conclusions: Use of home-based video-recordings for remotely rating motor function in PD is feasible, and requires study in a larger cohort. Correlation of video-based svUPDRS ratings with “traditional” in-person rating is good, and results of this pilot study will guide modifications in training participants and recording parameters. We predict that this approach will enhance data collection in PD clinical trials involving testing new therapeutics for motor control.
To cite this abstract in AMA style:
J. Carter, N. Hellmers, A. Hanineva, C. Henchcliffe. Testing feasibility and utility of remote data capture technology to assess Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/testing-feasibility-and-utility-of-remote-data-capture-technology-to-assess-parkinsons-disease/. Accessed November 5, 2024.« Back to 2016 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/testing-feasibility-and-utility-of-remote-data-capture-technology-to-assess-parkinsons-disease/