Session Information
Date: Tuesday, September 24, 2019
Session Title: Parkinsonisms and Parkinson-Plus
Session Time: 1:45pm-3:15pm
Location: Agora 3 West, Level 3
Objective: To evaluate whether implantation precision is related to the outcome of STN DBS.
Background: Accurate implantation of electrodes is important for the outcome of deep brain stimulation (DBS) treatment of Parkinson’s disease (PD). There is a need for data on the value of implantation precision.
Method: Hemibody data from STN DBS patients were divided into responders and non-responders based on the post-operative improvement on the UPDRS-III hemibody score. A Euclidean distance from the individual active contact points to the mean of all active contacts points was compared between responders and non-responders.
Results: Full data was available for 83 electrodes. The mean coordinates of the responders did not differ from the mean coordinates of the non-responders. The distance from the active contact to the mean of all active contacts was 2.2±1.1 mm (mean±SD) in the responder group and 3.2±1.4 mm in the non-responder group (p = 0.001).
Conclusion: No unidirectional targeting error was found to be related to clinical response. Increased random error (less precision) was associated with less clinical response.
To cite this abstract in AMA style:
T. Ten Brinke, V. Odekerken, P. Schuurman, R. de Bie. The effect of active contact localization on motor symptoms in deep brain stimulation of the subthalamic nucleus for Parkinson’s disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/the-effect-of-active-contact-localization-on-motor-symptoms-in-deep-brain-stimulation-of-the-subthalamic-nucleus-for-parkinsons-disease/. Accessed July 17, 2025.« Back to 2019 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/the-effect-of-active-contact-localization-on-motor-symptoms-in-deep-brain-stimulation-of-the-subthalamic-nucleus-for-parkinsons-disease/