The serum response factor SRF protect dopamine (DA) neurons in Parkinson’s disease partially by mediate autophagy through a beclin 1-dependent pathway
Objective: To investigate the level of serum response factor(SRF) in rotenone-induced Parkinson's disease(PD) model and PD patients, and explore the potential protective role and underlying…Creutzfeldt-Jakob disease presenting predominantly with movement disorder: A case report
Objective: To highlight that Creutzfeldt-Jakob Disease can present predominantly with movement disorder. Background: Creutzfeldt-jakob Disease (CJD) is a rapidly progressive spongioform degeneration of the brain…TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells
Objective: To investigate the effect of TNF on α-synuclein degradation and to explore the potential role of autophagy-lysosome pathway involved in this processs. Background: In…Predictive validity of statistical models of Parkinson’s disease progression
Objective: To develop statistical models of Parkinson's disease (PD) progression based on a transversal assessment and to explore its predictive value in a three-year follow-up.…Fall status and stepping response: Individuals with PD are differently influenced by side-affected
Objective: To identify differences in compensatory stepping responses (CSR) between Parkinson's disease (PD) fallers and non-fallers in response to external perturbations. Specifically, to investigate if…Examining the clinical profile of nelotanserin, a novel agent in development for Lewy body dementia
Objective: To examine the clinical profile of nelotanserin, a novel agent in development for the treatment of Lewy body dementia. Background: Although not FDA-approved for…Dopaminergic medicines are alternative drugs for treatment of motor disorders in ischemic stroke
Objective: To study the possibility of using levodopa and amantadine for the treatment of motor disorders in ischemic stroke after taking the standard treatment. Background:…Effects of videogame step training on gait adaptability in people with Parkinson´s disease – A randomized controlled trial
Objective: To evaluate the effect of home-based interactive videogame step training on gait adaptability performance in people with Parkinson's disease (PD). Background: The ability to…Medicinal cannabis for Parkinson’s disease: A survey of practices, beliefs, and attitudes among providers at NPF centers of excellence
Objective: To gather data on the cannabis-related prescribing practices, and views regarding potential risks and benefits of cannabis, among experts caring for patients with PD.…Effects of exercise intervention on balance and gait performance, and balance confidence in people with Parkinson’s disease – A meta-analysis
Objective: To examine the short- and long-term effects of exercise intervention on enhancing balance, and gait performance, and balance confidence in Parkinson's disease (PD) population,…
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