MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2016 International Congress

    The effect of dopaminergic therapy on stimulus-response learning and decision-making in Parkinson’s disease using fMRI

    P.A. MacDonald, N.M. Hiebert, K.N. Seergobin, A.M. Owen (London, ON, Canada)

    Objective: Our aim was to examine the neural correlates of stimulus-response (SR) learning in patients with Parkinson's disease (PD) on and off dopaminergic (DA) therapy…
  • 2016 International Congress

    Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease

    F. Hell, J.H. Mehrkens, A. Plate, K. Bötzel (München, Germany)

    Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…
  • 2016 International Congress

    The feasibility of measuring fatigability in early-stage Parkinson’s disease using functional MRI

    Y. Xing, N. Bajaj, S.T. Schwarz, D.P. Auer (Nottingham, United Kingdom)

    Objective: To investigate the effect of fatiguability on brain activation in people with Parkinson's (PwP) in comparison with healthy volunteers(HV). Background: Fatiguability, an objective decline…
  • 2016 International Congress

    Alterations in muscle synergies in early stage Parkinson’s disease

    J.F. Daneault, G. Vergara-Diaz, C. Adans-Dester, G. Ferreira-Carvalho, V.C.K. Cheung, P. Bonato (Charlestown, MA, USA)

    Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…
  • 2016 International Congress

    The patterns of olfactory function in Parksinson’s disease patients with mild cognitive impairment

    J.W. Park, H.K. Yoon, M.H. Park, D.Y. Kwon (Ansan, Korea)

    Objective: To examine relationship between olfactory dysfunction and PD-MCI, and investigated the patterns of olfactory function in subtypes of PD-MCI patients using the Korean version…
  • 2016 International Congress

    Levodopa impairs learning in healthy young adults: Implications for Parkinson’s disease

    P.A. MacDonald, A. Vo, K.N. Seergobin (London, ON, Canada)

    Objective: The objective was to investigate the effect of dopaminergic therapy on healthy young adults to test the dopamine overdose hypothesis. Background: Dopaminergic therapy improves…
  • 2016 International Congress

    Association or causation? Orthostatic hypotension and cognitive impairment in α-synucleinopathies: A systematic review

    S.J. Udow, A.E. Lang, M. Masellis (Toronto, ON, Canada)

    Objective: To systematically review the literature for evidence of an association between orthostatic hypotension (OH) and cognitive impairment (CI) in α-synucleinopathies and to discuss possible…
  • 2016 International Congress

    Circulatory levels of BDNF correlate with cognitive deficits in people with Parkinson’s disease

    H. Khalil, M.A. Alomari, O.F. Khabour, A. Al-Hieshan, J.A. Bajwa (Irbid, Jordan)

    Objective: The aim of this study was to examine the relationship of serum BDNF levels with cognitive function. Background: Brain-derived neurotrophic factor (BDNF) is essential…
  • 2016 International Congress

    Dopamine modulates learning conflicting action-valence associations in Parkinson’s disease

    N.C. van Wouwe, D.O. Claassen, J.S. Neimat, S.A. Wylie (Nashville, TN, USA)

    Objective: To investigate the effect of dopaminergic medication in Parkinson's disease (PD) on learning to act and learning to withhold action based on rewarding versus…
  • 2016 International Congress

    Plasma ceramides and glucosylceramides predict cognitive decline among cognitively normal Parkinson’s disease patients

    M.M. Mielke, C.E. Hagen, R. Savica, J.A. Syrjanen, X.M.T. Persson, C. Schulte, R. Dodel, M. Balzer-Geldsetzer, J.B. Schulz, K. Reetz, U. Wullner, A. Spottke, A. Storch, H.U. Wittchen, O. Riedel, E. Kalbe, S. Graber-Sultan, T. Gasser, D. Berg, I. Liepelt-Scarfone (Rochester, MN, USA)

    Objective: To determine whether plasma ceramides, glucosylceramides, and their ratios predict cognitive decline among cognitively normal Parkinson's disease (PD) patients. Background: There are no biomarkers…
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