The assessment of quality of life in patients with early and moderately advanced Huntington disease
Objective: The aim of the study was to determine if available quality of life related scales are useful to detect the deterioration of quality of…Verbal fluency deficits in essential tremor patients: Underlying structural changes
Objective: A disturbance of verbal fluency (VBF) in essential tremor patients compared to healthy controls is well described. The underlying structural alterations that a causative…Dorsolateral nigral hyperintensity on 3.0 tesla susceptibility-weighted imaging in idiopathic rapid eye movement sleep behaviour disorder
Objective: To assess the loss of dorsolateral nigral hypersensitivity (DNH), which seems to correspond to nigrosome-1, using susceptibility-weighted imaging (SWI) at 3.0 Tesla (T) in…Single unit activity of medial thalamus during goal-directed motor and cognitive behavior in patients with cervical dystonia
Objective: To 1) study neuronal activity of medial thalamic nuclei (MD, CM-Pf) and its role in cognitive and motor human activity and 2) evaluate neuronal…Comparative analysis of clinical and neuroimaging features of parkinsonism and dementia of Alzheimer’s type
Objective: Explore the features of cognitive disorders and neuroimaging features of Parkinson's disease (PD) and Alzheimer's disease (AD) in the comparative aspect. Methods: Study 64…Arterial spin labeling perfusion MRI compensate for other diagnostic tools in evaluation of Parkinson’s disease with dementia
Objective: To test usefulness of arterial spin labeling (ASL) perfusion MRI for diagnoses of Parkinson's disease (PD) with dementia. Background: Dopamine transporter (DAT) images may…Impulsive-compulsive behaviors in patients with Parkinson’s disease and demographically-comparable group of healthy controls
Objective: To assess patients with Parkinson's disease (PwPD) impulsive-compulsive behaviors (ICBs) prevalence compared to healthy controls (HCs) group, to analyze PD clinical features, ICBs risk…Inhibition of glucosylceramide synthase reduces pathology and improves cognition in synucleinopathy murine models
Objective: We investigated the merits of glucosylceramide synthase (GCS) inhibition as a potential treatment for synucleinopathies. Background: Mutations in GBA, the gene encoding glucocerebrosidase, are…Freezing of gait in Parkinson’s disease: A stopping deficit?
Objective: We evaluated the role of inhibition in freezing of gait, and related performance on a behavioral stopping task to the structural integrity of the…MRI signatures of the brain of Parkinson’s disease and idiopathic REM sleep behavioral disorder subjects
Objective: To characterize brain microstructural integrity, iron loads, and functional connectivity in 10 idiopathic rapid eye movement sleep behavior disorder (RBD), 10 Parkinson's disease (PD)…
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