Factors affecting the cardiac sympathetic denervation in autopsy confirmed dementia with Lewy bodies
Objective: To examine the relation among degeneration of the cardiac sympathetic nerve (CSN), clinical features and neuropathological findings in dementia with Lewy bodies (DLB). Background:…A heterozygous splicing mutation c.823-10G>T at the intron9/exon 10 of the MAPT gene in an Irish family with FTDP- 17
Objective: *Authors EMF and DAO contributed equally. To describe the phenotype of the second reported pedigree with the heterozygous splicing mutation c.823-10G>T at the intron…Differences in physicians’ understanding of biologic and biosimilar medicines in the USA and Europe
Objective: To evaluate differences in physicians' understanding of biologic and biosimilar medicines in the USA and Europe. Background: Biologic medicines, such as botulinum toxins and…Curcumin supplementation improves motor dysfunction in lipopolysaccharide induced Parkinon’s disease model: Possible biochemical, neurochemical and immunohistochemical alterations in rats
Objective: In the present study potential neuroprotective effects of curcumin were tested to determine if they could help to minimize microglia–mediated damage in single intranigral…AntiParkinsonian effects of the “radiprodil and tozadenant” combination in MPTP-treated marmosets
Objective: Investigate a combination of two clinically tested drugs, the NR2B antagonist Radiprodil and the A2A antagonist Tozadenant in unilaterally 6-OHDA-lesioned rats and in MPTP-treated…Engrailed enhances dopamine synthesis in healthy dopaminergic neurons
Objective: The aim of the present study was to further elucidate the role of Engrailed in dopamine neurotransmission. Background: Engrailed1 and Engrailed2, collectively Engrailed, are…Eight weeks of home-based balance training not as effective as therapist-based during dual tasks
Objective: To assess the effect of balance training on dual-tasking gait, and to investigate if a home-based programme is comparable to a therapist-supervised programme. Background:…Effects of safinamide in patients with Parkinson’s disease measured by Parkinson’s KinetiGraphTM
Objective: To objectively evaluate the effects of Safinamide in patients with Parkinson's (PD) by using the Parkinson's KinetiGraphTM (PKG), a newly developed tool for graphically…New therapeutic algorithm for abnormal posture in Parkinson’s disease and related disorders
Objective: To establish the simple therapeutic algorithm for abnormal posture in Parkinson's disease (PD) or related disorders. Background: Camptocormia or dropped head are sometimes accompanied…Creatine for patients with Parkinson’s disease: A meta-analysis
Objective: The aim of this systematic review and meta-analysis is to synthesize evidence from published randomized controlled trials (RCTs) about the efficacy of creatine for…
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