Beliefs and knowledge on Parkinson’s disease (PD) among people with PD, the public and traditional healers in Western Cape, South Africa
Objective: To determine belief systems and knowledge about PD among patients with PD, among the public and among traditional healers. Background: Parkinson's disease (PD) is…Progressive encephalomyelitis with rigidity and myoclonus (PERM) in an intellectually disabled patient initially misdiagnosed as neuroleptic malignant syndrome (NMS)
Objective: This is the first reported case of PERM made in a patient with profound mental retardation and we highlight the unusual features of his…The communicative effectiveness survey-revised (CESR): An objective measure of communicative participation for people with Parkinson’s disease
Objective: To study the item-level psychometric properties of the Communicative Effectiveness Survey-Revised (CESR), the first patient reported outcome measure for people with Parkinson's disease (PD)…The differentiated treatment of Parkinson’s disease in patients with concomitant diabetes mellitus(DM) type 2
Objective: To study the state of lipid metabolism in PD patients with concomitant type 2 diabetes with different glucose tolerance and the influence of the…Effect of dopamine and L-3,4 – dihydroxyphenylalanine in treatment of experimental parkinsonism
Objective: To study effect of dopamine and L-3,4 - dihydroxyphenylalanine in treatment of experimental parkinsonism. Background: Prospects of treatment of Parkinson's disease are also closely…Improving the experience of diagnosis in Parkinson’s disease
Objective: To identify areas in which patient experience of being diagnosed with Parkinson's can be improved. Background: Receiving a Parkinson's diagnosis can leave patients feeling…Hydrogen sulfide functions as a neuromodulator to regulate striatal neurotransmission in a mouse model of Parkinson’s disease
Objective: To Evaluate:prepared a MPTP/p induced mouse subacute model of PD, and explore the modulatory effect of H2S on monoamine and amino acid neurotransmitters in…Inhibition of cathepsin D enhances the autophagy lysosome pathway dysfunction and α-synuclein aggregation in experimental parkinsonism
Objective: To explore the mechanism of CTSD inhibition in the dysfunction of autophagy-lysosome pathway and aggregation of α-synuclein in Parkinson's disease. Background: α-synuclein, the main…Effect of repeated intravenous amantadine infusions in patients with Parkinson’s disease
Objective: To examine the long-term effect of repeated boosts of intravenous amantadine in patients with PD with and without response fluctuations and dyskinesias. Background: Amantadine…Computational assessment of calcium channel effects on subthalamic nucleus neuronal cells: Study of abnormal bursting patterns in Parkinson’s disease
Objective: Understanding the drug effects with respect to various ion channels on subthalamic nucleus (STN) cells is the key to safety pharmacology assessment. Here our…
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