Are Parkinson’s disease futility studies futile?
Objective: Revisit Phase II futility studies. Background: Published results of a Phase III trial of creatine monohydrate for Parkinson's disease (PD) in the presence of…DBS related on-state freezing of gait – A case series
Objective: To present the first ever case series of on-state freezing of gait (FOG) after DBS surgery using dose-cycle gait evaluation. Background: FOG is categorized…Can stimulation of deep brain tissue improve the expression of the mouth in Parkinson’s disease patients?
Objective: To observe if stimulation of deep brain tissue can improve expression of the mouth in Parkinson's disease patients. Background: Masked facies or hypomimia is…Electric stimulation of the nucleus subthalamicus is able to modulate prepulse inhibition. A pilot study in Parkinson´s disease
Objective: To evaluate if prepulse inhibition (PPI) is influenced by electrical stimulation in the Nucleus subthalamicus (STN) of patients with Parkinson´s disease (PD). Background: PPI…Evaluation of the accuracy of stereotactic DBS electrode implantation by post-operative image fusion
Objective: The precision in implantation of deep brain stimulation (DBS) electrodes based on pre-operative MRI planning is of utmost importance for the success of this…Wearable sensors and decision algorithms for advanced therapy referral in Parkinson’s disease
Objective: Pilot study to determine the impact of remote monitoring using objective, wearable sensors on the advanced therapy referral rate in patients with advanced Parkinson's…Assessment of freezing of gait in Parkinson’s disease patients treated with STN-DBS
Objective: To evaluate FOG in patients with PD treated with STN-DBS and to compare sensitivity of different assessments of FOG in this specific group of…Tourette syndrome treated by continuous electrical neuromodulation (DBS): Targeting the comorbidities?
Objective: To assess the response to deep brain stimulation (DBS) in refractory Tourette syndrome (rTS) of both tics and behavioural comorbidities. Background: Gilles de la…VOP/ZI deep brain stimulation for the relief of tremor in multiple sclerosis
Objective: To evaluate the therapeutic effect of electrical chronic stimulation of ventralis oralis posterior and zona incerta (VOP/ZI) in 3 subjects affected by severely disabling…The Catalan multiple system atrophy-registry (CMSAR)
Objective: To collect comprehensive and standardized clinical data and to create a repository of biological samples and cell lines from probable and possible MSA patients…
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