Deep brain stimulation of the dentate nucleus improves ataxia and modulates cortical excitability
Objective: To assess tremor and ataxia changes by dentate nucleus deep brain stimulation and evaluate how DBS could modulate cortical excitability seen in cerebellar stroke.…Fiberoptic endoscopic evaluation of swallowing findings in patients with Machado-Joseph disease
Objective: To describe the main findings of Fiberoptic endoscopic evaluation of swallowing (FEES) in patients with MJD. Background: Machado-Joseph disease (MJD) is a degenerative process…Abnormal findings in polisomnographic records of patients with spinocerebellar ataxia type 2 (SCA2)
Objective: The aim of this study was to assess the frequency of abnormal findings in sleep recordings of patients with SCA2. Background: Similar to other…Long-term impact of lead poisoning on neurologic function in children and adolescents
Objective: To elucidate (1) whether prolonged effects of lead exposure are persistently reflected by impaired neurological parameters and (2) whether these outcomes can be attributed…Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington’s disease gene carriers
Objective: Using positron emission tomography (PET) with [11C]IMA107, we investigated the in vivo expression of PDE10A in extra-striatal regions in a cohort of 12 early…Verbatim patient-reported outcomes and trails making test B (TMT-B) performance in the REACH2HD trial
Objective: Examine the relationship between Trails Making Test B (TMT-B) performance and bothersome cognitive complaints among Huntington Disease (HD) research participants in the REACH2HD randomized-controlled…Maintenance of balance function in patients with HD treated with deutetrabenazine, as measured by Berg balance test (BBT) in First-HD
Objective: To assess the effect of deutetrabenazine treatment on balance using the BBT in patients with HD in First-HD. Background: Patients with HD have disrupted…A health cost analysis for Huntington disease in Peru
Objective: To estimate economic costs of caring for an individual with Huntington disease from the patients and caregivers perspective. Background: Huntington disease (HD) is a…99mTc-TRODAT-1 SPECT findings in a patient with sporadic Creutzfeldt-Jakob disease
Objective: To report a case of sporadic CJD presenting insomnia,vertigo, ataxia and parkinsonism as first symptoms and describes the 99mTc-TRODAT-1 SPECT findings. Background: CJD is…Movement execution but not preparation modulates somatosensory temporal discrimination thresholds in healthy subjects
Objective: The aim of the study was to investigate in healthy subjects whether somatosensory temporal discrimination threshold (STDT) is influenced by movement execution and preparation.…
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