In idiopathic Parkinson’s disease: The effect of using L-dopa on peripheral nerves
Objective: Idiopathic Parkinson's disease (IPD) is a chronic neurodegenerative disorder. Most of the clinicians believe that it is limited with motor and cognitive disorders. However,…1 to 40 years later: Delayed effects of brain radiation presenting as parkinsonism
Objective: To report 3 adult cases of delayed radiation induced parkinsonism, with latency ranging from 1 to 40 years. . Background: Unequivocal radiation induced parkinsonism…The phenotypic and genetic features of myoclonus-dystonia in six Saudi Arabian kindreds
Objective: To study the motor symptoms, psychiatric and neuropsychological features and genetic findings of patients with familial dystonia with or without myoclonus in a movement…The interrater variability in clinical assessment of post-hypoxic myoclonus
Objective: To investigate the interrater variability in clinical assessment of acute post-hypoxic myoclonus (PHM) after cardiopulmonary resuscitation. Background: PHM is a clinical symptom that can…A phase 3, placebo-controlled study with an open-label extension: Sustained incobotulinumtoxinA efficacy in upper-limb post-stroke spasticity over 48 weeks
Objective: To assess the efficacy and safety of incobotulinumtoxinA for upper-limb post-stroke spasticity. Background: Botulinum toxin injections are a recommended therapy for limb spasticity. We…Tics exacerbations in middle-aged and older adults with Tourette syndrome: A case series
Objective: To describe five cases of adults with Tourette Syndrome (TS) who experienced exacerbations of their tics. Background: Tourette Syndrome is a life-long disorder, but…Tremor frequency by iPhone® applications: Correlation with EMG analysis
Objective: To compare tremor frequency obtained by EMG and accelerometry analysis with three iPhone® applications. Background: Frequency as a property of tremor is a vital…Analysis of LINGO1 and LINGO2 genes in essential tremor and Parkinson’s disease
Objective: We studied the involvement of LINGO1 and LINGO2 in Russian patients with ET and PD. Background: Genetics of ET is unclear. Three candidate loci…Comparing tremor- and non-tremor effects of ethanol in patients with essential tremor
Objective: To explore the relationship between self-reported non-tremor effects of ethanol and objective tremor severity in Essential Tremor (ET). Background: Ethanol has been demonstrated to…Modelling spinocerebellar ataxia 15 with iPS cell derived neurons
Objective: Here we set out to study the cellular pathology of ITPR1-deletions underlying SCA15 in a human model of iPSC-derived cortical neurons. Background: Spinocerebellar Ataxia…
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