- In vivo MRI detection of Parkinson’s disease associated degeneration in the lateral ventral tier of substantia nigra pars compactaObjective: To test a novel multimodal MRI approach for in vivo assessment of the subregion of substantia nigra pars compacta (SNpc) most vulnerable to Parkinson's…
- Comparison of Test Your Memory (TYM) and Montreal Cognitive Assessment (MoCA) measures in Parkinson’s diseaseObjective: We sought to determine: a) the ability of TYM to discriminate between PD patients with and without cognitive deficits b) equivalence between MoCA scores…
- Cognitive and behavioral problems in children and adolescents with myoclonus dystoniaObjective: To compare the neuropsychological and behavioral profile of A) children and adolescents with myoclonus dystonia (MD) to a healthy control group and B) MD…
- Treatment and diagnosis with the use of neuropsychological scale in patients with posttraumatic subcortical Parkinsonian dementiaObjective: To study the value of various neuropsychological scales to determine the degree of cognitive dysfunction in patients with posttraumatic subcortical Parkinsonian dementia, during the…
- Retrieval action verbs is impaired in Parkinson´s disease patients using a sentence completion taskObjective: Our aim is to investigate if action verb retrieval is impaired, compared to sensorial verbs using a sentence completion task in non-demented Parkinson´s Disease…
- Sensitivity of people with Parkinson’s to different intensities of emotions (SPiEs)Objective: To characterise the ability of individuals with Parkinson's to discriminate the six universal facial expressions. Background: People with Parkinson's (PwP) tend to have difficulty…
- The role of neuroinflammation in the development of Parkinson’s disease dementiaObjective: To evaluate, at post-mortem, the pattern and characteristics of neuroinflammatory change in Parkinson's disease (PD) brain and to assess its relationship with aberrant alpha-synuclein,…
- Effect of rivastigmine in Parkinson’s disease dementia – A logitudinal observational studyObjective: Outcome of Rivastigmine treatment in Parkinson's disease Dementia (PDD). Effect of treatment on cognition and Neuropsychiatric symptoms. To compare clinical global impression of Clinicians…
- Cognitive and behavioral side effects in patients treated with droxidopa for neurogenic orthostatic hypotensionObjective: To describe adverse behavioral symptoms attributed to droxidopa therapy for neurogenic orthostatic hypotension (nOH). Background: Droxidopa, a norepinephrine (NE) precursor, improves symptoms of neurogenic…
- Subthalamic neurons encode reward hypersensitivity and loss hyposensitivity in Parkinson’s patients with impulse control disordersObjective: 1) To determine if a subset of subthalamic nucleus (STN) neurons in Parkinson's disease (PD) patients modulate activity in response to valence-related stimuli (reward/punishment)…
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