- Physiotherapy can reduce the decline in functioning according to ICF framework in patients in early stage of Parkinson’s disease evolutionObjective: To investigate the effects of physiotherapy treatment on functioning according to International Classification of Functioning, Disability and Health (ICF) framework in patients in early…
- Role of the atypical vesicular glutamate transporter VGLUT3 in l-DOPA-induced dyskinesiaObjective: To evaluate the role of the atypical vesicular glutamate transporter 3 (VGLUT3) and the vesicular acetylcholine transporter (VAChT) in L-DOPA-induced dyskinesia. Background: Parkinson's disease…
- An ongoing phase 2, multi-centre, open-label, study of WTX101 in Wilson disease patients – Early observationsObjective: The aim of this ongoing study is to evaluate the efficacy and safety of WTX101 in newly diagnosed Wilson Disease patients. Background: WTX101 (bis-choline…
- Supplement use in PD is associated with delayed initiation of dopaminergic therapyObjective: To describe supplement use among early PD patients, and to determine its association with time to initiation of dopamine replacement therapy (DRT). Background: Earlier…
- Subcutaneous apomorphine reduces OFF time and dyskinesias and improves quality of life in Parkinson’s disease (PD) – 5-year follow-up of patients in GreeceObjective: To evaluate the long-term efficacy of subcutaneous apomorphine (APO) injection and APO infusion in controlling motor fluctuations and dyskinesias and the impact on quality…
- Effectiveness of a multidisciplinary PD clinic in improving quality of lifeObjective: To evaluate the effectiveness of a multidisciplinary PD clinic in a tertiary hospital in Hong Kong. Background: Parkinson's disease (PD) has been recognized as…
- Predicting medication reduction in Parkinson’s disease patients after deep brain stimulationObjective: To determine which factors predict medication reduction for Parkinson's disease (PD) patients after deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN). Background:…
- Nilotinib improves motor skills, cognition and autonomic function in open-label phase I clinical trial in Parkinson’s disease with dementia and Lewy body dementiaObjective: Nilotinib, a tyrosine kinase inhibitor (TKI) was examined with the aim of showing its effect on safety comparing a lower dose of 150mg (N=6)…
- Therapeutic yoga improves balance and balance confidence in Parkinson’s diseaseObjective: The objective of this study was to improve balance and balance confidence in individuals with Parkinson's disease (PD) following an 8-week therapeutic yoga intervention.…
- A phase II, pragmatic, randomized clinical trial on a high-intensity exercise and fall prevention boot camp for Parkinson’s disease: Signal of efficacyObjective: To determine if a high intensity exercise and fall prevention boot camp (HIBC) would produce greater benefit than a low intensity control (Fitness Counts…
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