Real world conversion of levodopa to a novel extended release levodopa preparation: Determining predictors and dose ratios
Objective: To determine predictors of response and conversion ratios for a novel extended release levodopa preparation. Background: A new extended release levodopa preparation, Rytary®, has…Altered resting-state functional interhemispheric connectivity in Parkinson’s disease
Objective: To examine direct interhemispheric functional connectivity (FCi) in Parkinson's disease (PD) during resting-state fMRI and to investigate the relations between observed connectivity changes and…The role of striatal dopaminergic terminals in early de novo PD patients with speech impairment
Objective: To assess the role of striatal dopaminergic terminals in early de novo (untreated) Parkinson's disease (PD) patients with impairment of speech. Background: Dopamine has…Dopaminergic and metabolic network activities in onset-related subtypes of Parkinson’s disease: A dual-tracer positron emission tomography study
Objective: The current study investigated the differences of dopaminergic and metabolic patterns between the young-onset subtype of Parkinson's disease (YOPD) and the late-onset subtype (LOPD)…Relationship between freezing and pedunculopontine nucleus’ size in Parkinson’s disease: Semi quantitative analysis based on MRI with modified FGATIR sequence
Objective: The aim of this study was to determine the possible relation between pedunculopontine nucleus' size (PPN) and occurrence of freezing in Parkinson's disease (PD).…Suppression of dyskinesia in Parkinson’s disease by electrical stimulation of dorsal subthalamic nucleus tissue
Objective: The objectives of this study were to investigate suppression of dyskinesia in Parkinson's disease (PD) patients who had previously undergone deep brain stimulation (DBS)…Impact of chronic LD treatment on metabolism, blood flow and blood-brain barrier permeability in the 6-OHDA rat model
Objective: To determine the effects of chronic LD treatment and induction of dyskinesias on cerebral metabolism, blood flow and blood-brain barrier permeability in 6-OHDA rat…Correlation between neuro-behavioral symptoms, cognition and gait in patients with dementia with Lewy bodies (DLB)
Objective: To determine the prevalence of neurobehavioral disturbances and their relationship to gait and cognitive impairment in DLB. Background: The recent literature has conceptualized that…Study of striatal dopamine transporter function in Alzheimer’s disease with parkinsonism
Objective: To clarify the pathological basis for Alzheimer's disease (AD) with parkinsonism using striatal dopamine transporter (DAT) scan. Background: Pathological basis for parkinsonism in AD…Synaptic biomarkers for cognitive decline in Lewy body dementias and Alzheimer’s disease. A mass spectrometry approach
Objective: The aim of our study is to understand the role of synaptic dysfunction in cognitive decline by comparing the whole proteome of Parkinson's disease…
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