Mov Disord Vol 31, Suppl 2 Archives - Page 35 of 207 - MDS Abstracts

2016 International Congress
Dysregulated macroautophagy and mitochondrial dynamics in PD with glucocerebrosidase mutations
S.H. Kuo, H. Li, A. Ham, M.M. Cheng, Y. Quan, D. Sulzer, G. Tang (New York, NY, USA)
Objective: To investigate markers of macroautophagy and mitochondrial dynamics in fibroblasts and postmortem brain of Parkinson's disease (PD) patients with glucoerebrosidase (GBA1) mutations and controls.…
2016 International Congress
Bcr-Abl tyrosine-kinase inhibitors (B-ATKI) and Parkinson’s disease (PD)
E.A. Shamim, S.F. Baker, F.F. Liu, K.K. Mane, J.G. Layug, S. Vupputuri, C.C. DiStasio, S.M. Khandhar, C. Neff, S. Van Den Eeden, C. Lungu, R. Cooley, H.S. Martel, C. Chen, J. Dorman, M.A. Sinkiewicz, J. Klingman (Largo, MD, USA)
Objective: Looking through the Kaiser Permanente National Parkinson's disease Registry, generated through the electronic medical records (EMR), we took a first step in looking at…
2016 International Congress
Reach-to-grasp impairments of both hands in individuals with Parkinson’s disease
S. Khacharoen, J. Tretriluxana, A. Pisarnpong, P. Chaiyawat (Nakhon Pathom, Thailand)
Objective: To compare the reach-to-grasp (RTG) planning, kinematics and coordination of the less- (left) and more affected (right) hand in Individuals with Parkinson's disease (PD)…
2016 International Congress
Micro-RNA in cerebrospinal fluid as a biomarker for early diagnosis, differential diagnosis and prognostic marker in Parkinson’s disease
A. Fischbach, A.E. Roser, F. Maass, M. Börger, M. Bähr, I. Zerr, A. Fischer, P. Lingor (Göttingen, Germany)
Objective: This study aims to identify specific micro-RNA (miRNA) patterns in cerebrospinal fluid (CSF) of patients with Parkinson's disease (PD) and to compare them with…
2016 International Congress
Histone deacetylase 4 is regulated by microRNA 128 in SH-SY5Y cells of Parkinson’s disease
J. Li, N. Xiong, H. Jiang, L. Liu, C. Han, K. Ma, X. Xu, Y. Shen, Y. Xia, L. Wang, S. Guo, J. Huang, T. Wang (Wuhan, People's Republic of China)
Objective: To explore the mechanisms and regulating effects of microRNA 128 in Parkinson's disease (PD). Background: PD is the second common progressive neurodegenerative disorder characterized…
2016 International Congress
Exploring aging-VMAT2 gene-rotenone interactions in a cell model for Parkinson’s disease
H. Jiang, J. Li, C. Han, K. Ma, L. Liu, Y. Shen, L. Wang, S. Guo, Y. Xia, J. Huang, T. Wang (Wuhan, People's Republic of China)
Objective: To develop a Parkinson's disease (PD) model based on aging, vesicular monoamine transporter 2 (VMAT2) gene susceptibility and chronic rotenone exposure in SK-N-SH cell,…
2016 International Congress
Falls in Parkinson’s disease: Beware the short, slow steps
A. Lieberman, A. Deep, S. Shafer, T. Lockhart (Phoenix, AZ, USA)
Objective: To determine if step length influence falls in Parkinson's disease (PD) patients. Background: Falls are major cause of disability in PD. The objective of…
2016 International Congress
Altered glutamate response and calcium dynamics in iPSC derived striatal neurons from XDP-patients
P. Capetian, N. Stanslowsky, E.M. Bernhardi, M. Naujock, K. Grütz, A. Domingo, P. Seibler, F. Wegner, C. Klein (Lübeck, Germany)
Objective: Our objective was to generate an in vitro model of XDP based on striatal neurons differentiated from induced pluripotent stem cells (iPSC), followed by…
2016 International Congress
A randomized, double-blind, placebo-controlled trial of deutetrabenazine for the treatment of tardive dyskinesia (ARM-TD)
H.H. Fernandez, S.A. Factor, R.A. Hauser, J. Jimenez-Shahed, W. Ondo, M.S. LeDoux, D. Shprecher, T. Simuni, D. Stamler, K.E. Anderson (Cleveland, OH, USA)
Objective: To determine the efficacy and safety of deutetrabenazine (DTB) as a treatment for tardive dyskinesia (TD). Background: There is no approved treatment for TD,…
2016 International Congress
Psychiatric profile in functional (psychogenic) jerky movement disorders
Y.E.M. Dreissen, T.J. van Trier, J.M. Dijk, D.C. Cath, M.A.J. Tijssen (Amsterdam, Netherlands)
Objective: To systematically assess the psychiatric profile in functional jerky movement disorders. Background: Less and less emphasis is currently placed on psychopathology in functional neurologic…