The sense of agency is altered in cervical dystonia
Objective: We investigated whether deficits in motor representation are associated with alterations of the sense of agency in dystonic patients. Background: Abnormalities of the cognitive…Epidemiological and clinical profile of essential blepharospasm and its response to treatment with TBA over a 11-year period
Objective: To report the epidemiological and clinical profile of patients with essential bleaphrospasm from the outpatient clinic of Movement Disorders of the Hospital de Clínicas…Direct comparisons for botulinum neurotoxins in movement disorders
Objective: To review clinical trials directly comparing botulinum neurotoxins (BoNT) for the treatment of movement disorders. To assess efficacy and safety from head-to-head clinical trials.…Pseudodystonic upper limb secondary to thalamic lesions: Usefulness of ultrasound-guided botulinum toxin treatment
Objective: Case reports. Background: Although botulinum toxin is routinely used as first-line treatment for focal dystonias, little is known about its usefulness in the treatment…Dystonia, myoclonus, and tremor without epilepsy associated with a mutation in STXBP1
Objective: Describe a presentation of abnormal movements associated with a mutation in STXBP1. Background: STXBP1, or the syntaxin binding protein 1 gene, is involved in…The serum response factor SRF protect dopamine (DA) neurons in Parkinson’s disease partially by mediate autophagy through a beclin 1-dependent pathway
Objective: To investigate the level of serum response factor(SRF) in rotenone-induced Parkinson's disease(PD) model and PD patients, and explore the potential protective role and underlying…Creutzfeldt-Jakob disease presenting predominantly with movement disorder: A case report
Objective: To highlight that Creutzfeldt-Jakob Disease can present predominantly with movement disorder. Background: Creutzfeldt-jakob Disease (CJD) is a rapidly progressive spongioform degeneration of the brain…TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells
Objective: To investigate the effect of TNF on α-synuclein degradation and to explore the potential role of autophagy-lysosome pathway involved in this processs. Background: In…Predictive validity of statistical models of Parkinson’s disease progression
Objective: To develop statistical models of Parkinson's disease (PD) progression based on a transversal assessment and to explore its predictive value in a three-year follow-up.…Fall status and stepping response: Individuals with PD are differently influenced by side-affected
Objective: To identify differences in compensatory stepping responses (CSR) between Parkinson's disease (PD) fallers and non-fallers in response to external perturbations. Specifically, to investigate if…
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