Treatment of OFF episodes in Parkinson’s disease: An evaluation of patient and caregiver insights
Objective: Evaluate patient and caregiver opinions into the treatment of OFF episodes in patients with Parkinson's disease (PD). Background: OFF episodes are fairly common in…Synaptic homeostasis in Parkinson’s disease: An high-density EEG study in different stage of the disease
Objective: In order to corroborate these findings, we submitted 29 Parkinson's disease (PD) patients with different stage of disease to an all-night high-density EEG (hd-EEG)…Detailed proteomic analysis of early PD brain highlights altered expression of mitochondrial proteins as an important event in sporadic PD
Objective: To uncover early pathogenic events occurring prior to neuronal loss and Lewy body formation in human PD brain. Background: In PD, pathological changes spread…Lrrk2 alleles modify host response to microbial infections
Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…Incidental finding of drug-induced movement disorder
Objective: Recognizing a drug-induced movement disorder is critical as only stopping using over the counter dopamine-blocking medications such as metoclopramide can reverse or improve clinical…Alcohol-responsive action myoclonus of the leg in prostate cancer: A novel paraneoplastic syndrome
Objective: To describe two patients with prostate cancer and identical phenotypes of likely paraneoplastic unilateral leg myoclonus. Background: Paraneoplastic movement disorders (PMDs) in prostate cancer…Sleep related disorders in subtypes of patients with Parkinson’s disease in the Tomsk region, Russia
Objective: To describe sleep related disorders (SRD) in Tremor Dominant (TD) and Akinetic Rigid (AR) patients with Parkinson's disease in (PwPD) subtypes evaluated at Movement…A pilot study of SD-809 (deutetrabenazine) in tics associated with Tourette syndrome
Objective: This study explored the safety, tolerability and preliminary efficacy of SD-809 (deutetrabenazine) in adolescents with moderate to severe tics associated with Tourette syndrome (TS).…Correlation between tremor severity of essential tremor and perpendicular displacement in digital spiral analysis
Objective: Using changes of perpendicular displacement in digital spiral drawing to evaluate the handwriting severity in essential tremor patients. Background: Essential tremor patients usually have…Phenotypes in Essential Tremor: Gait analysis and imaging study
Objective: If essential tremor (ET) is the most common movement disorder in adults, its pathophysiology remains poorly understood and few data are available as for…
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