Safinamide improves both motor and non-motor symptoms in fluctuating Parkinson’s Disease patients.
Objective: To investigate the efficacy of safinamide, compared to placebo, as add-on therapy to stable doses of levodopa, on both motor and non-motor symptoms in…Riding the puzzle: deep brain stimulation and the non-motor symptoms in Parkinson’s disease
Objective: To better understand the benefits of DBS in non-motor symptoms. Background: Parkinson's disease(PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons,…Parkinson Disease-Associated Polyneuropathy: A Biomarker of Disease Severity?
Objective: Objective: We sought to examine the association between Parkinson disease (PD) associated polyneuropathy (PD-PNP) and levodopa dose, age, and disease duration in a cross-sectional,…An association between impulse control disorders and dopamine agonists in Japanese patients with Parkinson’s disease.
Objective: To evaluate an association between impulse control disorders (ICDs) and dopamine agonists (DA) therapy in Japanese patients with Parkinson’s disease (PD). Background: ICDs such…Abnormal melatonin secretion rhythm and nocturnal polyuria in patients with Parkinson’s disease
Objective: To evaluate the association between melatonin secretion rhythm and nocturnal polyuria, and the pathophysiology of nocturnal polyuria in PD. Background: Patients with PD have…Parkinson’s Disease from the Patient Perspective
Objective: The purpose of this study was to describe the constellation of parkinsonian symptoms, as experienced by the patient. Background: For 200 years, the cardinal…A double-blind, randomized, placebo controlled study of botulinum toxin type A for limb pain in advanced Parkinson’s disease
Objective: To evaluate safety, tolerability and efficacy of botulinum toxin type A for limb pain in advanced Parkinson´s disease (PD). Background: Pain is a frequent…Association of pain in Parkinson’s disease with anxiety, depression and sleep quality: a cross-sectional study
Objective: To investigate the association of pain in Parkinson's disease (PD), including its clinical and descriptive subtypes, with anxiety, depression and sleep quality. Background: Pain is a common non-motor…Which clinical features predict progressive supranuclear palsy pathology? A clinicopathological study on 437 autopsy cases and a literature review
Objective: To identify clinical features and investigations which predict PSP pathology during lifetime in the largest pathology PSP cohort reported to date compared to autopsy…Evaluation of a Radiographic Marker as a Diagnostic Tool For Progressive Supranuclear Palsy
Objective: To evaluate the sensitivity and specificity of a radiographic marker, midbrain to pons ratio, in brain MRI of Progressive Supranuclear Palsy (PSP) patients as…
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