Development of nano-formulation containing crocetin for the protective and beneficial effect against 6-hydroxydopamine induced Parkinson’s disease model via altered the genetic backgrounds
Objective: Parkinson’s disease (PD) induced by the interaction between the number of factors viz., aging, genetics toxins, mitochondrial deformity and oxidative stress. Various evidences suggest…Genetic knock-down of HDAC4 attenuates rotenone-induced abnormal expression of α-synuclein by affecting autophagic flux in SH-SY5Y Cells
Objective: To assess whether histone deacetylase 4 (HDAC4) is related to the abnormal expression of α-synuclein (α-syn) via the autophagy pathway. Background: The overexpression and…Glut-1 deficiency: a case report
Objective: To report the case of a patient with refractory seizures who was diagnosed with Glut-1 deficiency. Background: Although Epilepsy is commonly diagnosed by child…Non-motor symptoms in ACDY5-associated disease
Objective: To describe non-motor symptoms in a case of ACDY5-associated disease. Background: The hereditary dyskinesia syndrome caused by an ACDY5 mutation was first described in…Impaired cerebral and systemic endothelial dysfunction in patients with restless legs syndrome
Objective: In this study, we aim to determine whether an association between RLS and endothelial dysfunction exists. Background: Restless legs syndrome (RLS) is a sleep…Design and personalisation of new upper-limb dynamic orthoses for dystonia and dyskinesia
Objective: The study proposes a method to obtain anatomically- and functionally-personalised orthotics for the dynamic postural control of the upper limb. Background: The orthotic treatment…Saving Veterans Time, Miles, and Money: Cost Analysis of Video Telemedicine Evaluation of Deep Brain Stimulation (DBS) candidacy at the VA
Objective: This study evaluated cost, time, and mileage saved utilizing video-telemedicine during the initial pre-surgical evaluation for deep brain stimulation as treatment for tremor at San Francisco VA…Evaluation of the short-term and long-term effects of an intensive multidisciplinary collective rehabilitation program over 5 weeks in Parkinson’s patients followed in Lyon
Objective: We studied the value of collective (8 patients per group) intensive multidisciplinary collective rehabilitation in the short and long term. Background: Numerous studies have proved…Barriers to exercise in newly diagnosed Parkinson’s disease
Objective: To evaluate and understand the perceived benefits and barriers towards physical activity in newly-diagnosed people with Parkinson’s disease (PwP). Background: The evidence base to…Exercise preferences of people with Parkinson’s disease: preliminary findings of a discrete choice experiment
Objective: To identify which exercise program attributes most commonly drive willingness of people with Parkinson’s disease (PD) to participate in evidence-based exercise programs. Background: A…
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