eEF1A2 promotes cell survival and protects against MPP+-induced apoptotic neuronal death through the PI3K/Akt/mTOR pathway
Objective: To assess the correlation of eEF1A2 and PI3K/Akt/mTOR expression and investigate the pro-survival role of eEF1A2 in NG108-15 rodent neuroglioma cells. Background: Eukaryotic protein…Exome sequencing in patients with impulse control disorders in Parkinson’s disease: a pilot study
Objective: To identify genetic variants associated with impulse control disorders (ICD) in Parkinson’s disease (PD) Background: ICD is frequently associated with dopamine agonist (DA) therapy…Alterations in lipid metabolism modify GBA1-mediated neurodegeneration in a Drosophila model of Parkinson’s disease
Objective: To understand how glucocerebrosidase (GBA1) mutations increase susceptibility to Parkinson's disease (PD). Background: Our understanding of the pathogenesis PD remains limited, and currently no…Longitudinal analysis of the relation of dopamine agonist use with impulse control disorders in Parkinson’s disease
Objective: To investigate the longitudinal relationship between dopaminergic therapies and impulse control disorders (ICD) in PD. Background: ICD are frequently associated with dopaminergic therapy, particularly dopamine…Predictive Ability of Clinical Timed Tests for Postural Instability and Gait Difficulty in Parkinson’s Disease
Objective: To identify clinical determinants for postural instability and gait difficulty in persons with Parkinson's disease (PD). Background: Gait deficits and postural instability in persons…Sports or no sports – is that the question in PD?
Objective: A multitude of risk factors or protective factors in developing Parkinson’s Disease (PD) are under discussion, as caffeine consumption or smoking .. Background: Frequent physical activity…Is There a Correlation Between Functional Capacity Upper Limbs and Falls Risk and Postural Instability in Parkinson’s Disease?
Objective: The goal of this study was to verify by a Brief Battery Functional Assessment (BBFA) the correlation between upper limb function skills with falls…The Adult Spasticity International Registry (ASPIRE) Study: Treatment Utilization Patterns in Patients Treated for Both Upper and Lower Limb Spasticity
Objective: To examine the treatment patterns of onabotulinumtoxinA utilization in patients treated for upper and lower limb spasticity, in combination, from the ASPIRE study (1…Tourettism associated with the Xq25 Microduplication Syndrome
Objective: To present a novel case of Tourettism emerging within the Xq25 microduplication syndrome. Background: Tourette syndrome (TS) is a childhood-onset neurobehavioral disorder hallmarked by…Postural control is maintained after a 8-months period of exercise in people with Parkinson’s disease
Objective: Our aim was to investigate the effects of different long-lasting exercises programs on the postural control in people with Parkinson’s disease (PD). Background: Postural…
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