5-year results from the NSTAPS trial: comparing bilateral deep brain stimulation of the globus pallidus pars interna versus the subthalamic nucleus for advanced Parkinson’s disease.
Objective: Comparing motor, cognitive, and psychiatric outcome 5 years after bilateral deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) and the subthalamic…Preliminary Report on the MAESTRO Study: A Pilot Study of Mirabegron and Behavioral Modification including Pelvic Floor Exercise for Overactive Bladder in Parkinson Disease.
Objective: To report enrollment and tolerability data of mirabegron treatment in PD patients with OAB. Background: Lower urinary tract symptoms in PD have an estimated…ON-time evolution following one-year open-label opicapone: BIPARK-I study
Objective: ON-time evolution following 1-year, open-label (OL), once-daily (QD) opicapone (OPC) treatment in patients with Parkinson’s disease (PD) on levodopa-therapy and with motor fluctuations. Background:…Associating patient impression of improvement with efficacy endpoints in Parkinson’s disease: A post-hoc analysis of a tozadenant study
Objective: To evaluate whether patient perceived improvement of Parkinson’s disease (PD) symptoms was associated with improvement in efficacy endpoints (mean daily OFF time and ON…Cardiac 123I-MIBG Scintigraphy, olfactory testing and transcranial sonography for differentiating between Parkinson’s disease and atypical parkinsonian syndromes during the early stage
Objective: To evaluate the utility of the combined use of cardiac metaiodobenzylguanidine (MIBG) scintigraphy, olfactory testing, and substantia nigra (SN) hyperechogenicity on transcranial sonography (TCS)…Post-movement beta rebound inhibits future movement
Objective: To evaluate the potential inhibitory effect of post-movement beta rebound (PMBR) on future movement production. Background: Changes in the cortical power of beta oscillations within the…Structural brain abnormalities associated with preclinical cognitive impairment in Idiopathic Parkinson’s Disease.
Objective: Using the Progressive Parkinson’s Initiative (PPMI) data, clinical and structural differences between individuals destined to develop PD cognitive impairment was defined. Background: Cognitive dysfunction…Multicenter Validation of Disease- related Parkinson’s disease pattern with Resting State functional MRI
Objective: To validate Parkinson’s Disease-related network topography characterized with resting-state functional MRI (rs-fMRI) in two multicenter based cohorts of idiopathic Parkinson’s disease (IPD) patients. Background:…In vivo mapping of nigro-striatal dopamine transporter (DAT) availability in early Parkinson´s disease patients using [18F]FE-PE2I and high-resolution positron emission tomography.
Objective: The objective of the present work was to evaluate in vivo with high resolution positron emission tomography (PET), the relative loss of the dopamine…Olfactory Impairment in Parkinson’s Disease and White Matter Abnormalities in Central Olfactory Areas
Objective: To determine white matter abnormalities in PD patients with various degrees of olfactory impairment. Background: Neuroimaging results of PD brain based on diffusion tensor…
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