Risk of Parkinson’s disease in zolpidem user: A systematic review and meta-analysis
Objective: To explore the association between zolpidem use and risk of Parkinson's disorder. Background: Zolpidem is commonly prescribed for the treatment of sleep disorder. Epidemiological…Reviewing the Clinical and Mutational Spectrum of SLC20A2 Mutations in Primary Familial Brain Calcification (PFBC) for MDSGene
Objective: Following the MDSGene protocol, we here present the clinical and mutational spectrum of SLC20A2 mutations, thereby adding the first gene found to be mutated…Spasmodic Dysphonia in Hereditary Spastic Paraplegia Type 7
Objective: To describe a case of spasmodic dysphonia associated with hereditary spastic paraplegia (HSP) type 7. Background: HSP is a heterogeneous group of inherited disorders…Progressive microstructural abnormalities of the occipital cortex in Huntington’s disease
Objective: To investigate the rate of longitudinal microstructural alterations in the occipital cortex in patients with different stages of Huntington’s disease (HD) compared to healthy…Demographic and Clinical Characteristics and Tetrabenazine (TBZ) Persistence in Patients With Huntington Disease (HD)-Associated Chorea
Objective: To characterize demographic and clinical characteristics of HD patients with chorea based on TBZ use status, and to examine treatment persistence with TBZ in…Parkinsonism in the very old – A clinicopathological study
Objective: To identify, spectrum of Parkinson variants, clinical features and course of disease in age > 80 year onset cases. Background: Old age is the…Regulation of aberrant striatal oscillations by glutamate receptor blockade in parkinsonian non-human primates
Objective: To study the abnormal striatal oscillations and regulation of striatal oscillatory activities by micro-infusion of glutamate receptor antagonist in the non-human primate model of…Interaction between PLK2 ( Polo-like kinase-2) and alpha-synuclein in the non-human primate MPTP model of Parkinson disease
Objective: The objective is to determine the levels and interactions between PLK2 and one of its main substrates, synuclein, in the non-human primate MPTP model of…Targeted overexpression of A53T-alpha-synuclein induces progressive neurodegeneration and electrophysiological changes of noradrenergic locus coeruleus neurons – a preclinical model of Parkinson’s disease
Objective: In our present study, we developed a new mouse model to study the time dependent effects of cellular A53T-α-synuclein overexpression in the locus coeruleus,…Prognostic relevance and predictive ability of data-driven PD subtypes in the Longitudinal and Biomarker Studies in Parkinson’s disease (LABS-PD)
Objective: To assess the prognostic relevance and predictive ability of a PD subtype classification system generated in LABS-PD cohort. Background: PD subtype classification systems have…
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