Prospective longitudinal CSF measurements and cognitive decline in GBA-associated Parkinsonism: not Abeta or Tau but Lewy body pathology?
Objective: To evaluate whether concomitant Ab and Tau pathology might contribute to the prominent cognitive decline in PD_GBA. Background: A considerable proportion of idiopathic Parkinson’s…Subjective cognitive complaints in Parkinson’s disease patients: what should we value ?
Objective: Access the relation between subjective cognitive complaints (SCC) and objective cognitive impairment in Parkinson’s Disease (PD) patients with and without Dementia and evaluate the…Cerebrospinal fluid lysosomal enzymes and cognition in Parkinson’s disease
Objective: To evaluate cerebrospinal fluid (CSF) levels of lysosomal enzymes and assess their relationship with cognition in PD as potential early biomarkers of cognitive failure.…Information Content of Spoken Language in Parkinson’s Disease Without Dementia
Objective: Investigate differences in spoken language content in Parkinson’s disease (PD) compared to older controls. Background: Conveying information is a primary goal of communication. PD language…Neuroimaging studies in familial forms of Parkinson’s disease: A systematic review
Objective: We aim to systematically review the current status of MRI, PET and SPECT imaging in asymptomatic (aPD) and symptomatic (sPD) genetic carriers of PD.…Screening of GBA and LRRK2 G2019S Mutations in Egyptian Parkinson’s Disease Patients
Objective: We aim to estimate the frequency of mutations in the glucocerebrosidase gene (GBA) and LRRK2 G2019S in a yet unstudied Egyptian Parkinson's disease population from the…Data driven analysis for exploring phenotypic differences in patients with Parkinson’s disease with or without genetic mutations.
Objective: To explore, using a data driven statistical analysis method, discriminating phenotype features of disease in a large group of patients with Parkinson’s disease (PD)…Dopamine agonist therapy mediates relationship between psychomotor inhibition and behavioral impulsivity in Parkinson’s disease.
Objective: Evaluate relationship between psychomotor inhibition and behavioral impulsivity in Parkinson’s disease (PD). Background: Impulse control disorders can be challenging iatrogenic effects of dopamine agonist…The role of habenula and amygdala dysfunction in Parkinson’s disease patients with punding
Objective: To assess whether a functional dysregulation of the habenula and amygdala, as modulators of the reward brain circuit, contributes to Parkinson’s disease (PD)-punding. Background:…Objective measurement of upper extremity bradykinesia using the keyboard-based dexterity test
Objective: To objectively assess the bradykinesia of upper extremity using the Objective Movement Disorder Measurement (OMDM)-Dexterity test Background: Bradykinesia is one of the clinical hallmarks…
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