Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy
Objective: We aimed to develop AAV-based models of MSA Background: Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by a combination of autonomic…Gut Microbiota in Multiple System Atrophy
Objective: To investigate the gut microbiome and metabolome in MSA Background: Experimental models of prion-like cell-to-cell transfer of alpha-synuclein(AS) and its ability to spread from the…Evaluation of mitochondrial dysfunction in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy
Objective: The aim of the present study is to investigate mitochondrial functioning in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy…Anatomical predictors of survival in PSP: thalamic collapse towards the end of life
Objective: To correlate anatomical changes with time to death in PSP. Background: Many advances have been made in progressive supranuclear palsy (PSP) since it was first described…Parkinsonism in Human African Trypanosomiasis: Clinical course, imaging findings and treatment-related challenges.
Objective: To present the clinico-imaging progression of parkinsonism from Human African Trypanosomiasis (HAT; sleeping sickness), and discuss the diagnostic and treatment challenges. Background: East African…Patient characteristics that impact caregiver burden in Parkinson’s disease in Singapore
Objective: The primary aim of this study was to identify patient characteristics that impact the caregiver burden in Parkinson’s disease (PD) in Singapore Background: PD…A national Swedish self-management program for people with Parkinson’s disease – patients and relatives view
Objective: To identify and describe experiences that people with PD and their relatives after participation in the self-management intervention NPS (National Parkinson School) find valuable for managing daily life. Background:…Redefining social work for Parkinson’s: the development of a model of care for specialized support in the clinic, community and home
Objective: The development of a dynamic, multimodal social work program model for individuals, caregivers and families living with Parkinson’s disease Background: Patients living with Parkinson’s…The effect of deep brain stimulation in a computational model of essential tremor
Objective: This study aimed to better understand the mechanism underlying the pathological brain activity observed in essential tremor (ET) and the effect of thalamic deep…Deep Brain Stimulation for Parkinson Disease before L-dopa treatment: experience in three cases.
Objective: The goal of these case series is to investigate the possibility of deep brain stimulation (DBS) prior to L-dopa treatment in young Parkinsson…
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