Medication optimization in Parkinson’s disease patients with ON-state freezing using objective gait assessments
Objective: To determine whether objective gait assessments could guide therapeutic decision making in Parkinson’s disease (PD) patients reporting freezing of gait (FOG) in the levodopa-ON…Diplopia: An Interesting Complication of Dropped Head Syndrome
Objective: To describe an interesting case of new-onset diplopia due to loss of compensation for trochlear nerve palsy as a result of dropped head in…Efficacy of IncobotulinumtoxinA for the Treatment Of Shoulder Spasticity
Objective: To evaluate efficacy of botulinum toxin for shoulder spasticity using a post-hoc analysis. Background: Botulinum toxin has been shown to be effective for treating…Basal Ganglia Circuits for Motor and Behavioral, Emotional Performances
Objective: The present study aimed to identify which neurons in the basal ganglia (BG) target dopaminergic or GABAergic neurons in SN pars compacta (SNc) or…A randomized, double-blind, placebo-controlled study of the D1 receptor antagonist ecopipam for children and adolescents with Tourette syndrome
Objective: To investigate the efficacy and safety of the selective dopamine D1 receptor antagonist ecopipam in children and adolescents with Tourette Syndrome (TS). Background: Dysregulation…Clinical and demographics of cervical dystonia related to the direction of the neck movement
Objective: The objectives of this report is to survey whether the type of torticollis (i.e. rotation, retrocolis and anterocolis) is related to the clinical characteristics…Dystonia-like phenotype in a DYT1 rat model after peripheral trauma
Objective: Establishment and characterization of a DYT1 rat model with dystonia-like movements after sciatic nerve crush injury. Background: Penetrance of DYT1 dystonia is markedly reduced…The Volatility of Local Field Potential Oscillations in Dystonia and Parkinson’s disease
Objective: To assess the volatility of low frequency (4-12Hz) and beta-band (13-30Hz) oscillations in local field potentials (LFPs) in dystonia and compare this to LFPs…Trisomy 8 Mosaicism and dystonia: a THAP1 overdose?
Objective: We report a case of Trisomy 8 Mosaicism (T8M, Warkany Syndrome) with craniocervical and hand dystonia, an hitherto unreported disease association. Background: T8M is…Differences between Hemifacial spasm with or without neurovascular conflict. Therapeutic implications with botulinum toxin type A.
Objective: To evaluate the presence of possible clinical differences between patients with HS with and without neurovascular conflict (NVC +, NVC-) and their therapeutic response…
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