Frontal-subcortical cognitive impairments in Parkinson’s patients with freezing of gait
Objective: To evaluate the relationship between frontal-subcortical cognitive dysfunctions and freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a complex and multisystem…The increased α-syn expression inhibits exosomal secretion
Objective: Exosomes, nano-sized extracellular vesicles, play an important role in many physiological processes in the central nervous system. Recently, we and others have demonstrated that…Soluble TREM2 and Central and Peripheral Inflammatory Biomarkers in Parkinson’s Disease
Objective: Given that Parkinson's disease (PD) may be associated with TREM2 and given that a soluble TREM2 (sTREM2) isoform has been described as elevated in…Association between serum Vitamin D levels and Parkinson’s disease: A systematic review and meta-analysis
Objective: The aim of this systematic review and meta-analysis was to evaluate the association between serum vitamin D levels and the risk and severity of…Quantitative Keyboard Tapping Measurement Correlates with Electrophysiological Changes in STN LFPs of PD Patients Treated with L-dopa Better Than UPDRS Subscores
Objective: Reliable and objective assessment of the symptoms of patients with Parkinson’s disease (PD) and the correlation of the measures with neural patterns is important…Saccades in Parkinson’s disease: Hypometric, slow, or maladaptive?
Objective: Quantitatively study visually-guided saccades (VGS) in Parkinson’s disease (PD). Background: Visuomotor deficits such as hypometric VGS are present in PD despite the retained ability…Evaluation of Parkinson’s Disease Psychosis Requires Structured Questioning of Patients and Caregivers
Objective: To determine the relationship between the patient and caregiver experience of the psychotic features of Parkinson's disease psychosis (PDP) reported to call center healthcare…What can we learn from fMRI capture of visual hallucinations in Parkinson’s disease?
Objective: To describe the patterns of brain functional changes when visual hallucinations (VH) occur in patients with Parkinson's disease (PD). Background: With disease progression, PD…A Psychometric Analysis of the MDS UPDRS-II and III in Early Parkinson’s disease: Do the Numbers Add Up?
Objective: Our objective was to explore the psychometric evidence for the use of the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part II…A German-Austrian multicenter, non-interventional, prospective study for the treatment with abobotulinumtoxinA injections in naïve and previously treated patients suffering from cervical dystonia
Objective: In this prospective, multicenter, non-interventional study (NCT01840462) the primary objective was effectiveness of abobotulinumtoxinA in BoNT treatment-naïve and previously treated subjects after two injection…
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