A 15-year review of a movement disorder database in Singapore
Objective: To establish the prevalence and demographical characteristics of patients seen in a Movement Disorders (MD) Centre. Background: Movement disorders contribute to a significant proportion…Vertical and horizontal eye movements in a large cohort of early manifest Huntington’s disease: Evidence from ENROLL-HD
Objective: To determine, in a very large sample, how different types of eye movement are differentially impaired in early manifest HD, and determine whether vertical…Prevalence of Single Nucleotide Polymorphisms (SNPs) rs362307 or rs362331 in Patients with Huntington’s Disease
Objective: An observational research study is being conducted in patients with Huntington’s disease (HD) to determine the frequency with which the thymine (T) variant of…An extraordinary cause of psychosis: Anti-NMDA receptor encephalitis
Objective: Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is an autoimmune encephalitis affecting predominantly young females. Background: It is characterized with neuropsychiatric symptoms, including personality changes, psychosis, autonomic…Are Lewy bodies associated with sympathetic pathology in dementia subjects?
Objective: Determine if Alzheimer disease (AD) subjects with Lewy bodies show sympathetic cardiac denervation. Background: Comorbid Lewy body (LB) pathology is very common in AD,…Creating a safe home for Parkinson’s disease patients: Designed principles for modifications
Objective: To proposed the design principles for home modification in Parkinson's disease based on home visit program. Background: Falling is a significant cause of morbidity…Pre-supplementary Motor Area Contributes to Motor Aspects of Sequential Risk-Taking
Objective: To determine the causal role of pre-supplementary motor area in risk-taking behavior during sequential decision making. Background: A recent functional magnetic resonance (fMRI) study…Increased Risks of Botulinum Toxin Injection in Patients with Hypermobility Ehlers Danlos Syndrome: A Case Series
Objective: To report increased risks of Botulinum Toxin Injection for cervical dystonia and migraine in patients with Hypermobility Ehlers Danlos Syndrome. Background: Ehlers-Danlos syndrome (EDS)…Comparative study of non-motor symptoms in patients with progressive supranuclear palsy and age, gender, duration of illness matched patients with Parkinson’s disease
Objective: To assess the frequency of NMS in PSP and compare them to age, gender and duration of illness matched PD patients. Background: Non-motor symptoms…A longitudinal study of brain quantitative MRI analysis before and after diagnosis of progressive supranuclear palsy
Objective: We analyzed longitudinal change in MRI imaging in PSP from the period before clinical diagnosis. Six patients with clinically diagnosed PSP including 1 case…
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