MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    7 years later, are the Tomlinson’s levodopa dose equivalencies proposed consensual?

    E. Dellapina, F. Ory-Magne, A. Sommet, V. Rousseau, D. Devos, S. Thobois, L. Defebvre, C. Brefel-Courbon, JC. Corvol, O. Rascol, F. NS-PARK/FCRIN Network (Toulouse, France)

    Objective: (i) To collect all the levodopa equivalent doses (LED) formulae and references used in clinical trials in Parkinson’s disease (PD) since the publication of…
  • 2018 International Congress

    Comparison of low versus high frequency stimulation on stuttering in Parkinson’s disease patients with bilateral subthalamic nucleus deep brain stimulation

    O. Jitkritsadakul, K. Boonpang, R. Bhidayasiri (Bangkok, Thailand)

    Objective: The objective of this study was to identify the prevalence of stuttering in PD patients with bilateral STN DBS compared to medically-treated PD (PD-MED)…
  • 2018 International Congress

    Evaluation of the interaction between safinamide and opicapone in Parkinson’s disease patients with fluctuations

    J. Garcia-Caldentey, MA. Prats-Sedano, I. Legarda-Ramirez, E. Estelrich-Peyret, B. Vives-Pastor, PJ. Garcia (Palma de Mallorca, Spain)

    Objective: To describe and to evaluate a Balearic ongoing Parkinson's disease (PD) Project to evaluate the efficacy and tolerance of the interaction between safinamide and…
  • 2018 International Congress

    VY-AADC01 gene therapy in Parkinson’s disease: Interim results of the on-going Phase 1b PD-1101 trial

    P. Larson, K. Bankiewicz, A. Van Laar, R. Richardson, B. Ravina, A. Kells, B. Boot, A. Martin, M. Thompson, C. Christine (San Francisco, CA, USA)

    Objective: Evaluate the safety of VY-AADC01, an AAV2 gene therapy vector with human aromatic L-amino acid decarboxylase (AADC) administered bilaterally to the putamen using intraoperative…
  • 2018 International Congress

    Efficacy of opicapone in Parkinson’s disease patients with ‘early’ motor fluctuations: UPDRS-II and III analysis from the BIPARK-I double-blind experience

    G. Ebersbach, J. Ferreira, F. Stocchi, R. Costa, E. Arbe, J-F. Rocha, P. Soares-da- (Beelitz, Germany)

    Objective: To evaluate the impact on UPDRS-II and III in levodopa-treated Parkinson’s Disease (PD) patients with ‘early’ motor fluctuations. Background: Opicapone (OPC), a novel once-daily…
  • 2018 International Congress

    Use of safinamide: A clinical practice review of 2 year experience

    C. Borrue-Fernandez (San Sebastian Reyes, Spain)

    Objective: Review the clinical use, efectivity and side efects in a population based cohort. Background: Safinamide is an oral, once a day adjunctive therapy for…
  • 2018 International Congress

    The Effect of Short Pulse Width Settings on Speech in Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s disease

    V. Dayal, T. Grover, E. Tripoliti, P. Limousin, T. Foltynie (London, United Kingdom)

    Objective: To compare perceptual characteristics and intelligibility of speech in Parkinson's Disease (PD) patients with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) in the acute setting…
  • 2018 International Congress

    Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial

    M. Schwarzschild, E. Macklin, R. Bakshi, S. Bhattacharyya,, R. Logan, A. Ascherio; on behalf of the Parkinson Study Group SURE-PD Investigators (Boston, MA, USA)

    Objective: To investigate whether women and men with Parkinson's disease (PD) may differ in their biochemical and clinical responses to long-term treatment with urate-elevating inosine.…
  • 2018 International Congress

    Effects of progressive resistance and flexibility exercise program of trunk on static and dynamic stability for Parkinson’s disease

    M. Lee, C. Youm, M. Son, H. Park, Y. Kim (Busan, Republic of Korea)

    Objective: The purpose of this study was to analyze the effects of progressive resistance and flexibility exercise of the trunk on static and dynamic stability…
  • 2018 International Congress

    Bdnf rs6265 and Other Variants Predict the Efficacy of Levodopa Monotherapy in Early-Stage Parkinson’s Disease

    C. Sortwell, P. Auinger, J. Goudreau, B. Pickut, M. Hacker, P. Charles, J. Lipton, A. Cole-Strauss, J. Elm, D. Fischer (Grand Rapids, MI, USA)

    Objective: To determine whether relatively prevalent variants in the gene for brain-derived neurotrophic factor (Bdnf) are associated with differential efficacy of levodopa or other dopaminergic…
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