Pallidal beta bursts in Parkinson’s disease and Dystonia
Objective: The aim of this study is to test whether prolonged beta burst duration is disease-specific for Parkinson's disease when compared to oscillatory activity in…The Gut Microbiota in a Canadian Parkinson’s Disease Cohort
Objective: To compare the gut microbiota between PD patients and matched controls in a Canadian cohort and to examine correlations between microbes and disease parameters…Distinct effects of apathy and dopamine on effort-based decision making in Parkinson’s disease
Objective: To determine if disrupted effort-based decision making (EBDM) underlies the syndrome of apathy in PD, and whether this disruption is modulated by the dopaminergic…The Effect of Sleep Deprivation on Short-Term Memory and Emotion of Rotenone Treated Zebrafish Model of Parkinson Disease
Objective: We investigated the long-term consequences of sleep deprivation on short-term memory and emotion using a rotenone treated zebrafish model of Parkinson disease. Background: Parkinson…Non-motor outcomes of subthalamic DBS in PD depend on the location of volume of activated tissue
Objective: To investigate the impact of stimulation location on non-motor symptoms (NMS) in PD patients with DBS in the subthalamic nucleus (STN) via an analysis…Is repetitive transcranial magnetic stimulation an effective tool to treat pain in Parkinson’s Disease?
Objective: An open label pilot study designed to assess safety and efficacy of repetitive transcranial magnetic stimulation(rTMS) to treat pain in Parkinson’s Disease. Background: Pain…Commonalities of prodromal non-motor symptoms between movement disorders
Objective: This study reviewed and compared evidence of nonmotor symptoms in prodromal phases in movement disorders including Parkinson disease, Atypical Parkinsonism (MSA, DLB, PSP), Huntington…Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synuclenopathies
Objective: We have investigated whether deposits of phosphorylated α-synuclein might be present in pancreatic tissue of subjects with synucleinopathies. Background: Parkinson’s disease patients experience a…Effect of Urinary Dysfunction on Fatigue Syndrome in Parkinson’s disease
Objective: to investigate the relationship between urinary dysfunction and fatigue syndrome in Parkinson`s disease Background: Fatigue syndrome (FS) is an overwhelming sense of tiredness, lack…Validation of protein phosphatases that regulate the LRRK2 phosphorylation cycle
Objective: To identify and validate candidate phosphatases regulating the LRRK2 phosphorylation cycle. Background: Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are one…
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