The severity of motor symptoms and depression are the higher predictor for the decrease in daily living activities independence in people with Parkinson’s disease
Objective: The purpose of this study was to identify among several motor, cognitive and mental measures which has higher power to predict the reduction in…Surface Modified Solid Lipid Nanoparticles for the targeted delivery to brain: Management of HIV-1 Associated Dementia
Objective: In this study, nifedipine loaded solid lipid nanoparticles (SLN) were developed for targeting drug into the central nervous system, the site of action of…A53T mutant human α-synuclein BAC transgenic mice as a model for Parkinson’s disease
Objective: The aim of this study is to create mouse models reproducing the course of PD pathology and symptoms. Background: Parkinson's disease (PD) is a…Evidence based management of Normal Pressure Hydrocephalus: Lessons and future directions
Objective: To present the methodology and management tree of patients referred to the Henry Ford NPH conference for an evaluation from 2003 to 2017. Background:…Cerebellar signs in progressive supranuclear palsy
Objective: To present a patient with cerebellar ataxia and a pathologically confirmed diagnosis of PSP. Background: Progressive supranuclear palsy (PSP) is an atypical form of…MSA Preliminary Panamerican Report
Objective: To report the results of the PAN American MSA (PANMSA) database Background: Multiple system atrophy (MSA) is a rare neurodegenerative disease and coordinated efforts…Serum insulin-like growth factor-1 levels in parkinsonism or dementia disorders
Objective: To investigate serum insulin growth factor-1 (IGF-1) levels in neurodegenerative disease and to correlate clinical parameters. Background: IGF-1 is highly expressed in the central…Rapamycin for treating MSA: A preclinical proof of concept study
Objective: To assess the effects of rapamycin on motor behavior, α-synuclein burden and surrogate markers of neurodegeneration in a transgenic mouse model of multiple system…Assessment of CSF biomarkers clinical value in Progressive Supranuclear Palsy
Objective: To evaluate diagnostic and prognostic usefulness of a panel of CSF biomarkers in PSP patients presenting with Richardson’s Syndrome (RS). Background: PSP is a…Finger Tapping Profile in “On State” PD Patients
Objective: We intent to explore the tapping profile in PD patients in "ON state" compared to controls in repetitive trials to clarify if motor control…
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