Non-motor symptoms in patients from the Catalonian Multiple System Atrophy Registry (CMSAR)
Objective: To assess non-motor symptoms (NMS) and their demographic and clinical correlates in MSA patients included in the CMSAR. Background: NMS are an important and…ARISE study: Study Design and Baseline Characteristics for a Phase 2 Trial of the Anti-Tau Antibody ABBV-8E12 in Progressive Supranuclear Palsy
Objective: This double-blind, placebo-controlled phase 2 study (M15-562 ARISE study, NCT02985879) assesses the safety and efficacy of ABBV-8E12 treatment in patients with progressive supranuclear palsy…Motor and cognitive deficits in a mouse model of tauopathy with tau isoforms imbalance: Potential therapeutic strategies
Objective: This work investigates motor phenotypes and neurochemical changes in a mouse model of tauopathy linked to tau mis-splicing. We sought to validate a potential…Midbrain/pons area ratio and clinical features predict the prognosis of PSP
Objective: This study aims to characterize the natural history of PSP and to find predictors of shorter survival and early institutionalization including neuroimaging biomarkers. Background:…Affective impairment and emotional tone of early Richardson’s syndrome and Progressive Supranuclear Palsy with predominant parkinsonism: The role of Alexithymia and Anhedonia
Objective: To define qualitative and quantitative differences of alexithymia and anhedonia among Progressive Supranuclear Palsy (PSP) with predominant parkinsonism (PSP-P), Richardson’s syndrome (PSP-RS) and Parkinson’s…Effects of multi-session repetitive transcranial magnetic stimulation on performance of motor control and dynamics of spontaneous brain activity in multiple system atrophy
Objective: To explore the effectiveness of repetitive transcranial magnetic stimulation (rTMS) on performance of motor control and dynamics of spontaneous brain activity in multiple system…Chronological view of peak and diphasic dyskinesia, wearing off and freezing in Parkinson’s disease: 1212 Korean population
Objective: To evaluate the gross chronological trend of 4 motor complications - peak dose dyskinesia, diphasic dyskinesia, wearing off and freezing. Background: Dyskinesia, wearing off…What strategies do Parkinson’s disease patients use for getting out of bed? Preliminary results from multisite wearable sensors analysis
Objective: To classify PD patients’ getting out of bed strategies using multisite wearable sensors. Background: Getting out of bed represents a major challenge for Parkinson’s…Determinates and predictors of quality of life improvements after subthalamic deep brain stimulation in Parkinson’s disease
Objective: To detect the related factors and possible predictors to QoL improvement for those PD patients one year after STN DBS. Background: Subthalamic deep brain…Sing to Beat Parkinson’s®: A Group Singing Intervention for People with Parkinson’s and their Carers
Objective: To improve the quality of life (QoL) of People with Parkinson’s (PwP) and their carers using a group singing intervention Background: As Parkinson’s disease…
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