Low-Fat Versus Ketogenic Diet In Parkinson’s Disease: A Pilot Randomized Controlled Trial
Objective: To compare the plausibility, safety, and efficacy of a low-fat, high-carbohydrate diet versus a ketogenic diet in a hospital clinic of PD patients. Background:…A Phase 2 Efficacy Study of CX-8998, a Potent and Selective T-Type Calcium (Cav3) Modulator in Parkinson’s disease Tremor (PDT) Patients: Design and Dose-Selection Rationale
Objective: The objective of this study is to access the efficacy of CX-8998 using the MDS-UPDRS Tremor Score (MDS-UPDRS-TS) and a digital biomarker platform, while…Motor and non-motor correlates of APOE-ε4 mediated cerebrospinal fluid concentrations of amino acids and monoamine metabolites in dementia with Lewy bodies compared with Alzheimer’s dementia and healthy controls
Objective: To study associations of cerebrospinal fluid (CSF) amino acids and monoamine metabolites with motor and non-motor features in dementia with Lewy bodies (DLB) compared…The possible neuroprotective potential of galantamine along with soya-lecithin and hydroxychloroquine against ICV-STZ induced cognitive dysfunction in rats
Objective: The present study investigates the possible neuroprotective potential of galantamine with soya-lecithin and HCQ against intracerebroventricular streptozotocin (ICV-STZ) induced memory impairment in a rat…Interaction between mGluR5 and NR2B is increased in 6-OHDA parkinsonian rats with L-dopa-induced dyskinesiaInteraction between mGluR5 and NR2B is increased in 6-OHDA parkinsonian rats with L-dopa-induced dyskinesia
Objective: In this study, we verified whether the interaction of mGluR5 and NR2B exerts an important effect on the development of LID. Background: L-dopa is…A framework to facilitate competence in practice for Parkinson’s Disease Nurse Specialists in the United Kingdom
Objective: To determine if the current Parkinson's Disease Nurse Specialist (PDNS) competency framework 2nd Edition 2008 (1) for nurses working in the management of Parkinson's…Knowledge of Parkinson’s Disease in Urban Population of Kyrgyz Republic
Objective: To assess public knowledge of Parkinson's disease (PD) in an urban population in Kyrgyz Republic. Background: Poor awareness and knowledge regarding PD among the…The role of Genes and Gene x Environment Determinants of Stress in the pathogenesis of Functional Neurological Disorders
Objective: The aim of the current study was to evaluate the association between common single nucleotide polymorphisms (SNPs) at the level of genetic loci involved…The comparison of the clinical characteristics and treatment outcomes between non-troublesome and troublesome hemifacial spasm in Thai patients
Objective: To compare the clinical characteristics and treatment outcomes after injection of botulinum neurotoxin (BoNT) type A between non-troublesome and troublesome hemifacial spasm (HFS) in…Cortical thinning as a neuroimaging marker of cognitive decline in X-linked dystonia-parkinsonism
Objective: To investigate whether alterations of cortical thickness correspond to cognitive dysfunction in XDP patients. Background: X-linked dystonia-parkinsonism (XDP) is a severe, hereditary movement disorder…
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