Determining the effect of the HNMT, STK39 and NMD3 polymorphisms on the incidence of Parkinson’s disease, amyotrophic lateral sclerosis and multiple system atrophy in Chinese populations
Objective: To investigate associations between 3 variants (HNMT Thr105Ile, STK39 rs2390669, and NMD3 rs34016896) and PD, multiple system atrophy (MSA) as well as amyotrophic lateral…SIRT1/AMPK pathway is involved in neuroprotective effects of resveratrol on MPTP-induced neuron loss
Objective: The present study was carried out to observe the neuroprotective effects of RV on MPTP-induced mouse model of PD, and explore its potential neuroprotective…Variants in MCCC1/LAMP3 and DGKQ Identified Through GWAS are Not Associated with PD in a Malaysian Malay Cohort
Objective: To investigate the association between variants in MCCC1/LAMP3 (rs12637471, rs12493050, rs10513789) and DGKQ (rs11248060) with PD in a Malay cohort. Background: Previous genome-wide association…PTRHD1 loss-of-function mutation in an African family with parkinsonism and intellectual disability
Objective: To investigate the clinical features and identify the disease-causing gene in a black South African family affected by juvenile-onset parkinsonism and intellectual disability. Background:…Effects of N-methyl-D-aspartate receptor antagonist in Parkinson’s disease with dementia
Objective: We conducted this longitudinal study to confirm the efficacy of memantine for PDD by analyzing comparative changes in regional cerebral blood flow (rCBF) and…The use of DaT-SPECT scanning in the differential diagnosis of Parkinsonism: Are guidelines being followed?
Objective: The aim of this study was to assess the adherence of a UK National Health Service (NHS) Parkinson’s disease service to National Institute for…Non-invasive, automated corneal nerve quantification reveals neurodegeneration in Parkinson’s disease: A potential novel imaging biomarker
Objective: The aim of the study is to use automated analysis of corneal confocal microscopy (CCM) images to allow rapid and reliable quantification of corneal…Identifying the neural correlates of doorway freezing in Parkinson’s disease
Objective: We aimed to combine a previously validated virtual reality gait paradigm with functional Magnetic Resonance Imaging (fMRI) to investigate the neural correlates underlying doorway-provoked…Characteristics of brain mri in patient with Parkinson’s disease
Objective: To investigate the characteristics and brain MRI findings in patient with Parkinson’s Disease Background: Parkinson's Disease is a chronic, progressive neurodegenerative disease that is…Effects of subthalamic nucleus deep brain stimulation in Parkinson’s disease are mediated by a prefronto-cerebellar-striatal loop
Objective: To determine DBS-related changes of a motor network using resting state fMRI in PD patients with chronic STN-DBS. Background: In Parkinson’s disease (PD), dopamine…
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