PTRHD1 loss-of-function mutation in an African family with parkinsonism and intellectual disability
Objective: To investigate the clinical features and identify the disease-causing gene in a black South African family affected by juvenile-onset parkinsonism and intellectual disability. Background:…Effects of N-methyl-D-aspartate receptor antagonist in Parkinson’s disease with dementia
Objective: We conducted this longitudinal study to confirm the efficacy of memantine for PDD by analyzing comparative changes in regional cerebral blood flow (rCBF) and…The use of DaT-SPECT scanning in the differential diagnosis of Parkinsonism: Are guidelines being followed?
Objective: The aim of this study was to assess the adherence of a UK National Health Service (NHS) Parkinson’s disease service to National Institute for…Non-invasive, automated corneal nerve quantification reveals neurodegeneration in Parkinson’s disease: A potential novel imaging biomarker
Objective: The aim of the study is to use automated analysis of corneal confocal microscopy (CCM) images to allow rapid and reliable quantification of corneal…Identifying the neural correlates of doorway freezing in Parkinson’s disease
Objective: We aimed to combine a previously validated virtual reality gait paradigm with functional Magnetic Resonance Imaging (fMRI) to investigate the neural correlates underlying doorway-provoked…Characteristics of brain mri in patient with Parkinson’s disease
Objective: To investigate the characteristics and brain MRI findings in patient with Parkinson’s Disease Background: Parkinson's Disease is a chronic, progressive neurodegenerative disease that is…Effects of subthalamic nucleus deep brain stimulation in Parkinson’s disease are mediated by a prefronto-cerebellar-striatal loop
Objective: To determine DBS-related changes of a motor network using resting state fMRI in PD patients with chronic STN-DBS. Background: In Parkinson’s disease (PD), dopamine…A cortical neural signature of motor interruption in patients with Parkinson’s disease and freezing of gait
Objective: To investigate whether cortical oscillations involved in sensorimotor and perceptual processes [alpha (8-12 Hz), low beta (13-20 Hz) and high beta (21-35 Hz)] change…Microstructural Changes in Normal Appearing White Matter in Parkinson’s Disease (PD) Correlate with Motor, Tremor, and Neuropsychiatric Scores
Objective: To determine if microstructural changes in the normal appearing white matter of PD are associated with clinical manifestations of disease. Background: White matter (WM)…Subthalamic Nucleus Local Field Potential Beta Activity in Chinese Advanced PD Patients
Objective: To test if the β oscillations of subthalamic nucleus (STN) local field potential (LFP) in Chinese advanced Parkinson’s disease (PD) patients are similar with…
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