Effect of Post-Operative Symptomatic Lead Edema Associated with Subthalamic Deep Brain Stimulation On Clinical Outcomes
Objective: To assess whether development of post-operative symptomatic edema around deep brain stimulation (DBS) leads impacts clinical outcomes. Background: Post-operative symptomatic delayed edema around the…Swimming in PD patients with STN-DBS: A pilot exploratory study
Objective: Patients with PD frequently complain of losing abilitiy to swim. Our aim was to test the swimming abilities of our patients with bilateral STN-DBS…Propionibacterium acnes Infection with Intracerebral Abscess in Deep Brain Stimulation
Objective: Propionibacterium acnes infection in DBS patients has distinct characteristics that distinguish it from the most commonly associated bacteria in postoperative wound infections, Staphylococcus aureus.…Microelectrode recording for optimization of the long-term outcome in subthalamic deep brain stimulation for Parkinson’s disease
Objective: To evaluate influence of microelectrode recording (MER) on clinical outcome of subthalamic deep brain stimulation (DBS STN) in patients with Parkinson's disease (PD). Background:…Modified Frameless Stereotaxy for Gene Therapy in Pediatric Movement Disorder Patients
Objective: We have developed a modified frameless stereotaxic system for viral vector delivery of gene therapy in pediatric movement disorder patients with congenital enzyme deficiency.…Non-motor symptoms in Spinocerebellar ataxia, multiple system atrophy and Idiopathic late-onset cerebellar ataxia
Objective: Recent studies suggest that non-motor symptoms (NMS) including urinary disorders, erectile dysfunction in men, orthostatic hypotension, sleep disruption, constipation, depression and anxiety are common…Cerebellar Ataxia case series study from southern Spain: Clinical and molecular description
Objective: Describe clinical features of a Cerebellar Ataxia non-Friedreich case series from southern Spain, and their molecular diagnosis. Background: Cerebellar Ataxias are a highly heterogeneous…Identification of modifiers of the age of onset variance and disease progression in a Dutch cohort of Machado-Joseph disease patients
Objective: In this project, we aim to establish correlations between the length of the CAGexp, AO, and disease progression based on International Cooperative Ataxia Rating…Transcriptional profiling of peripheral blood monocytes from child Friedreich’s ataxia patient: New molecules and patterns of gene expression
Objective: To explore peripheral biomarkers related to Friedreich's ataxia and identification of pathophysiological insights of complex phenotype Background: Friedreich's ataxia(FRDA) causes nervous system damage and…Sydenham’s Chorea: Realities and Challenges in Sub-Saharan Africa
Objective: The aim of this study was to describe the epidemiological, clinical, paraclinical and evolutive aspects of Sydenham's chorea. Background: Sydenham's chorea is a rare…
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