Three-year follow-up of a patient with a rare combination of taupathy (PSP) and synucleopathy (MSA)
Objective: We couldn't find an article showing that MSA and PSP appeared simultaneously in the same patient in the english literature. We wanted to present…Carrier Mediated Delivery System Bearing Dopamine for Effective Management of Parkinsonism
Objective: In the present investigation, amino acid coupled liposomes bearing dopamine-HCl were prepared to deliver drug to the brain utilizing receptor-mediated transcytosis for effective management…The role of mitochondria in modifying penetrance of Parkin gene variants
Objective: To understand whether mitochondrial DNA (mtDNA) mutation load can modify the penetrance of variants in the Parkinson’s disease (PD) causing gene PRKN (Parkin), in…The SUNRISE-PD Study, a clinical trial of AXO-LENTI-PD: a CNS-directed gene therapy for the treatment of Parkinson’s Disease
Objective: This presentation will provide an overview of the design and key objectives of the SUNRISE-PD study. Background: Parkinson’s disease (PD) is caused in part,…Continuous dopaminergic treatment with levodopa/carbidopa intestinal gel in multiple system atrophy: report of three patients
Objective: To evaluate the effect of continuous dopaminergic treatment with levodopa/carbidopa intestinal gel (LCID) on motor and non-motor symptoms in multiple system atrophy (MSA) patients.…Plasma-based circulating long non-coding RNA AS-Uch1 as a novel diagnostic biomarker for Parkinson’s disease
Objective: The study aimed to validate plasma-based circulating long non-coding RNA (lncRNA) as biomarker for the diagnosis of Parkinson's disease (PD). Background: Parkinson's disease (PD) is…Bilateral INO in PSP
Objective: We describe and demonstrate a patient with PSP who had bilateral internuclear ophthalmoplegia (BINO) with intact convergence on exam. Background: A thorough eye movement…NEUROPSYCHIATRIC SYMPTOMS IN EARLY TO ADVANCED PATIENTS WITH THE RICHARDSON’S SYNDROME VARIANT OF PROGRESIVE SUPRANUCLEAR PALSY
Objective: To know prevalence of neuropsychiatric symptoms in Progressive Supranuclear Palsy along disease stages. Background: Neuropsychiatric symptoms are common features in patients with Progressive Supranuclear Palsy…Cerebellar involvement in progressive supranuclear palsy and corticobasal degeneration
Objective: To investigate cerebellar involvement in vivo in patients with corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) using [18F]FDG PET. Background: Cerebellar ataxia is…Impact of overweight and obesity on functional and clinical outcomes of early Parkinson’s disease
Objective: To determine whether being overweight or obese contributes to disease progression and functional status in Parkinson’s disease (PD). Background: While the tendency of PD…
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