Per-oral image guided gastrojejunostomy insertion for levodopa-carbidopa intestinal gel in Parkinson’s disease is safe and may be advantageous
Objective: We describe a case series of 12 patients requiring administration of levodopa-carbidopa intestinal gel (LCIG) who had their tube placed by per-oral image guided…Safety and effectiveness of levodopa-carbidopa intestinal gel for advanced Parkinson’s disease : a large single-center study
Objective: To describe adverse events (AEs) associated with levodopa-carbidopa intestinal gel (LCIG) treatment and the main reasons for treatment discontinuation. We also assessed the effectiveness…To compare early / late onset MSA from the PAN American MSA (PANMSA) database
Objective: Compare two different cohorts of patients with the same pathology differentiated by age of onset. Background: Multiple system atrophy (MSA) is a rare neurodegenerative…Neuroanatomical and clinical predictors of pain in patients with early de novo Parkinson’s disease
Objective: We investigated associations between clinical features, neuroanatomical changes and pain in early de novo Parkinson’s disease (PD) patients. Background: Pain is a common and…Serum uric acid levels and cognitive function in Parkinson’s disease
Objective: To compare serum uric acid (sUA) levels in Parkinson’s disease (PD) subjects to cognitive function. Background: Reduced sUA levels have been reported in individuals…Deep Brain Stimulation as second line advanced treatment for PD after LCIG
Objective: Staging of advanced treatments for Parkinson's disease such as levodopa–carbidopa intestinal gel infusion (LCIG) and Deep brain stimulation (DBS) Background: Device-aided therapies for Parkinson’s…Bilateral vestibulopathy due to neurosarcoidosis mimicking Parkinsonian syndrome
Objective: We here describe a patient with neurosarcoidosis presenting with progressive gait disturbance that mimics Parkinsonian syndrome. Background: Neurosarcoidosis can show various neurological complications; however,…Towards unobtrusive Parkinson’s disease detection via motor symptoms severity inference from multimodal smartphone-sensor data
Objective: To provide clinically-corroborated evidence of the Parkinson’s disease (PD) diagnostic potential of machine learning-based approaches for motor symptoms severity inference via multimodal data, passively…Premature State of Oligodendrocytes Potentially Provides Critical Period for Extracellular Pathological α-Synuclein to Invade Oligodendrocyte Lineage Cells
Objective: Multiple system atrophy (MSA) is pathologically characterized by accumulation of misfolded α-synuclein (α-syn) in oligodendrocytes (OLGs), which is known as glial cytoplasmic inclusions (GCIs).…Gaze – evoked nystagmus in PSP patients: Is it really atiypical? A case series of eight patients
Objective: To present eight patients with progressive supranuclear palsy (PSP) syndrome and horizontal, gaze-evoked nystagmus (GEN), a finding hitherto assumed atypical for PSP[1]. Background: The…
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