The study of the role of genetic risk factors in levodopa-induced dyskinesia development in Russian patients with Parkinson’s disease: a pilot study
Objective: The aim of our study is to search for genetic risk factors for the development of motor side effects of dopaminergic therapy, such as…Virtual Assessment of LRRK2 Carriers to Optimize Research in Parkinson Disease (VALOR-PD): A Comparison to Traditional Cohorts
Objective: To compare a national virtual cohort of LRRK2 G2019S carriers, identified via a personal genetics company, to existing traditional cohorts. Background: Advancements in personal…Biomarker Discovery in Parkinson’s disease using Machine Learning on Public Multi-omic Datasets: A Pilot Study
Objective: In this study, we use machine learning (ML) as a framework for biomarker studies to assess if multiple modalities in the same model perform…The ROPAD (Rostock International Parkinson’s Disease Study) study: Towards defining the genetic epidemiology of the disease
Objective: ROPAD is an international, multicenter, epidemiological study that aims at a better understanding of the contribution of genetics to Parkinson’s disease (PD) based on…Type-3 Metabotropic Glutamate Receptors and Parkinson’s Disease: Preclinical Studies and Human Genetics
Objective: In a MPTP mice model of toxicological parkinsonism we examine whether the presence or absence of mGlu3 receptors is neuroprotective. We also evaluted association…Effects of exosomes devised from dopaminergic neurons overexpressing α-synuclein on autophagy and inflammation in microglia
Objective: The aim of this study was to investigate whether the exosomes secreted by dopaminergic neurons over-expressing α-synuclein could regulate the inflammation of microglia via…The Influence of 3-Phenoxybenzoic Acid in Dopaminergic Degeneration
Objective: 3-phenoxybenzoic acid (3-PBA) is a metabolite of Fenpropathrin (FEN). The emphasis of this paper is on the relationship between 3-PBA and Dopaminergic Degeneration. Background:…Quantitative susceptibility mapping images for the parcellation of the Subthalamic Nucleus: a possible role for targeting Deep Brain Stimulation
Objective: To investigate the iron distribution in STN in PD patients using QSM images. Background: Subthalamic Deep Brain Stimulation (DBS) is considered an effective treatment…Right hemispheric β-amyloid deposition associates with freezing of gait in Parkinson’s disease
Objective: To investigate regional cerebral deposition of β-amyloid in patients with Parkinson's disease (PD) who have freezing of gait (FoG). Background: FoG is one of…Retinal thinning and disease worsening in Lewy body diseases
Objective: To assess longitudinal changes of retinal thickness measurements and their role as biomarkers of disease progression in patients with Lewy body diseases (LBDs). Background:…
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