Oral treatment of the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS) with the neuro-inflammation inhibiting compound PRI-003
Objective: Demonstration of beneficial effects of neuro-inflammation inhibition for the treatment of amyotrophic lateral sclerosis (ALS). Background: Neuro-inflammation and immune-inflammatory processes are characteristics of the…Undiagnosed Neuropathology In Fallers: Findings from a 10-year Autopsy Series
Objective: To examine the range of neuropathology in people who die from a fall compared to those who die in alternate circumstances. Background: The neural…Are functional movement disorder phenotypes or age at onset correlated with perfectionist personality trait or history of abuse?
Objective: To assess if the phenotype or age at onset of Functional movement Disorders (FMD) vary as a function of presence of a perfectionist personality…Are New York City rail tracks harbingers for Parkinson’s disease?
Objective: To describe the clinical features of 7 New York City Metropolitan Transit Authority (NYC MTA) rail-track workers with Parkinson’s disease (PD) presenting to a…Role of Sex in Parkinson’s Disease Progression
Objective: To investigate the sex differences for disease progression in Parkinson’s disease (PD). Background: Prevalence and symptom profile in PD differ between women and men.…Prevalence of Neuropsychiatric Symptoms in the Prodromal Stages of Dementia with Lewy Bodies and Parkinson’s Disease Dementia
Objective: Investigate neuropsychiatric features of prodromal stage dementia among individuals diagnosed with Lewy body disease. Background: There has been minimal investigation into the prodromal features…Impact of Obstructive Sleep Apnea on Cognitive and Motor Functions in Parkinson’s Disease Patients
Objective: We conducted this systematic review and meta-analysis to assess the impact of OSA on cognitive and motor disorders in PD patients. Background: Parkinson’s disease…Predicting dementia in the first 6 years of Parkinson’s disease in the ICICLE-PD cohort
Objective: To determine which baseline cognitive tests in newly diagnosed participants with Parkinson’s disease (PD) predict conversion to dementia (PDD) within six years. Background: Cognitive…Decreased Regional Cholinergic Signaling in Parkinson’s Disease
Objective: To identify regions of decreased cholinergic signaling in Parkinson's disease (PD) participants relative to cognitively normal controls as measured by positron emission tomography imaging…Serum microRNA-29 family as potential biomarkers for cognitive impairment in Parkinson’s disease
Objective: To examine whether miRNA-29s (miR-29s) in serum could be used as biomarkers for either Parkinson’s disease with dementia (PDD) or Parkinson’s disease with mild…
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