A combined imaging based biomarker for Parkinson’s disease using diffusion kurtosis and quantitative susceptibility mapping
Objective: We aimed to investigate the utility of combined quantitative susceptibility mapping (QSM) and diffusion kurtosis imaging (DKI) as complementary tools in characterizing pathological changes…Deficient interhemispheric connectivity underlies movement irregularities in Parkinson’s disease
Objective: The aim of this study was to investigate whether impaired execution of drawing spirals relates to deteriorations in interregional connectivity. Background: Movement execution is…Influence of deep brain stimulation on premotor-motor interaction in patients with Parkinson’s disease
Objective: To investigate the interaction between subthalamic nucleus (STN), dorsal premotor (PMd), and primary motor cortex (M1) in patients with Parkinson’s disease (PD) in vivo by coupling…COVID-19 PANDEMIC: SYMPTOMS PERCEPTIONS FROM PARKINSON’S DISEASE PATIENTS
Objective: Our study aimed to evaluate PD patients’ perception regarding clinical aspects, physical activity and restricted access to medication during the pandemic. Background: Several countries…Effects of Parkinson’s disease on blur-driven and disparity-driven vergence eye movements
Objective: Visuomotor functions required for depth and dimensionality perception are significantly affected in a large number of patients with Parkinson’s disease (PD). Vergence is a…Brain MRI morphological changes in different self-reported sleep disturbances in PD patients
Objective: Our study explored associations between a variety of sleep-related problems and grey matter alterations in PD. Background: Sleep disturbance is a common non-motor feature…Plasma Neurofilament Light Chain Level and Orthostatic Hypotension in Early Parkinson Disease
Objective: To delineate the impact of non-motor markers (REM sleep behavior disorder (RBD), orthostatic hypotension (OH), cardiac sympathetic denervation, hyposmia) on neuronal injury in early-stage…Gait impairment as predictor of falls in patients with early Parkinson’s disease
Objective: To prospectively investigate disease progression in the early-stage Parkinson’s disease (PD) patients who fall (PD-Falls) and do not fall (PD-NoFalls) in the fifth year…Hearing Impairment was not associated with Dream Enactment Behavior and Parkinsonism in the Population: a CLSA Prospective Study
Objective: To assess the associations of hearing function with the progression of parkinsonism in a population-based prospective study. Background: Hearing impairment is a common symptom…Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…
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