High intensity exercise improves Sleep EEG Delta Power in Parkinson’s Disease
Objective: This novel study tests the hypothesis that 16 weeks of high-intensity exercise rehabilitation combining resistance training plus body-weight interval training, compared with a sleep…Locus coeruleus volume is reduced in Parkinson disease-related orthostatic hypotension.
Objective: To test whether structural pathology of the locus coeruleus (LC) is associated with orthostatic hypotension (OH) in Parkinson disease (PD). Background: OH is an…Intermittent theta burst stimulation over primary motor cortex ameliorates physical fatigue in Parkinson’s disease patients
Objective: To evaluate the effect of a single intermittent theta burst stimulation (iTBS) session on objective markers of physical fatigue of fatigue in patients with…Behavioral effects of stimulated dopamine release and D2-like receptor displacement in Parkinson’s patients with impulse control disorder
Objective: To evaluate behavioral effects of stimulated dopamine (DA) release in Parkinson’s disease (PD) by assessing D2/3 receptor (DA-R) displacement on PET imaging Background: Previous…Mobile application for assessing the likelihood of developing depression in patients with Parkinson’s disease
Objective: To develop a mobile application for assessing the likelihood of developing depression in patients with Parkinson's disease (PwPD), taking into account the number of…The Impact of Back and Neck Pain in Parkinson’s Disease: The PD-PAIN Study
Objective: To determine the prevalence of back and neck pain (BNP) in Parkinson’s Disease (PD) patients and the proportion of patients seeking invasive treatments for…A corneal nerve density possible progression biomarker in Parkinson’s disease (PD) patients: pilot study
Objective: To evaluate corneal sub-basal nerve plexus density in PD compared to age-matched healthy subjects using confocal microscopy Background: Cornea is the most densely innervated…HbA1c correlates with motor and cognitive outcome scores in patients with Parkinson’s disease and type 2 diabetes.
Objective: The objective of this study was to investigate the relationship between glycated haemoglobin (HbA1c) levels in blood and clinical outcomes (MDS-UPDRS III, MDS-UPDRS IV,…Do Parkinson’s disease medications have an effect on gut microbiome? A case-control study
Objective: To investigate the difference in the gut microbiota between drug-naïve and medicated PD patients and focus on the association between gut microbiota and anti-PD medications. Background:…Characterization of a mouse model of PDE10A-related autosomal-dominant movement disorder.
Objective: To characterize a newly generated mouse model of the movement disorder caused by PDE10A pathogenic mutation F300L. Background: Phosphodiesterase 10A (PDE10A) is a striatal…
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