Defining and restoring the underlying neural circuitry of hypersexuality in Parkinson’s Disease
Objective: To define the neural circuitry underlying hypersexuality in Parkinson’s disease and to provide novel therapeutic options by employing neuromodulatory techniques. Background: The balance between…The effect of rasagiline on nocturnal hypokinesia: the analysis of the Nocturnal Hypokinesia Questionnaire (NHQ)
Objective: To identify the effect of rasagiline on nocturnal hypokinesia based on Nocturnal Hypokinesia Questionnaire (NHQ). Background: Nocturnal hypokinesia refers to the difficulty or the…Early Synucleinopathy is Associated with Differential Regulation of Neurotransmission and Immune Related Genes
Objective: Identification of gene expression changes in the rat substantia nigra pars compacta (SNpc) associated with early alpha-synuclein (a-syn) inclusion formation. Background: Accumulation of intracellular…A randomized clinical trial (RCT) to evaluate the effects of safinamide on apathetic non-demented Parkinson’s disease patients
Objective: To evaluate the safety and effects of add-on safinamide on apathy in patients with Parkinson’s disease (PD). Background: Apathy is highly prevalent and disabling…WATCH-PD: Baseline Phenotype and Longitudinal Digital Assessments in Early PD
Objective: To provide a longitudinal profile of early Parkinson’s (PD) disease progression using clinical and digital measures, and to evaluate the extent to which digital…Beneficial effects of cinnamaldehyde in orofacial dyskinesia in haloperidol-induced rat model
Objective: This investigation evaluates the effect of CA in orofacial dyskinesia in haloperidol-induced rat male model Background: Orofacial dyskinesias are involuntary repetitive movements of the…Mapping Side Effects in Deep Brain Stimulation – Different Approaches, Different Problems.
Objective: This study aims to evaluate different strategies to map DBS‑induced side‑effects regarding their ability to create anatomically plausible stimulation maps and to predict side‑effect…Automated error detection when applying the protocol for the monitoring of motor function in patients with Parkinson’s disease using smartwatches.
Objective: To validate an automatic classification system for the identification of errors in the performance of standardized MDS-UPDRS III exercises by using inertial sensors from…Lack of immunogenicity of incobotulinumtoxinA in pediatrics: A pooled analysis
Objective: To present pooled data analyses of the immunogenicity of incobotulinumtoxinA (INCO) in pediatrics. Background: BotulinumtoxinA (BoNT-A) is used to treat several chronic pediatric conditions,…A second level neuropsychological battery for Parkinson’s Disease. Normative data from the Italian population.
Objective: The main purpose of this work is to propose modern Italian co-normed data for a battery of ten widely used neuropsychological tests for Parkinsons’…
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