MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2022 International Congress

    Phosphorylated α-synuclein at serine residue 129 decreased in Parkinson’s disease patients taking 250mg of daily niacin for six months

    C. Wakade, M. Seamon, S. Purohit, J. Morgan, R. Chong (Augusta, USA)

    Objective: The main objective was to determine if α-synuclein could be modulated by niacin supplementation, contributing to improved Parkinson’s disease (PD) symptoms. Background: Niacin supplementation…
  • 2022 International Congress

    Automated quantification of facial bradykinesia through video in de-novo Parkinson’s disease

    M. Novotný, H. Růžičková, E. Růžička, P. Dušek, J. Rusz, T. Tykalová (Prague 6, Czech Republic)

    Objective: The purpose of this study was therefore to develop a fully automatic video-based hypomimia assessment tool and estimate the prevalence and characteristics of hypomimia…
  • 2022 International Congress

    Clinical and genetic research in a large Ukrainian family with autosomal recessive hereditary spastic paraplegia

    A. Orlacchio, M. Stasi, A. Stigliano, M. Miele, F. Gaudiello, A. Meyyazhagan (Rome, Italy)

    Objective: To perform a clinical and genetic analysis of a large Ukrainian pedigree emigrated in Italy with autosomal recessive hereditary spastic paraplegia (ARHSP). Background: HSPs…
  • 2022 International Congress

    Deep Brain Stimulation for Rare Neurodegenerative Diseases: Three-Center Experience

    N. Durmaz çelik, B. Samanci, G. Yalçın çakmaklı, A. Aksoy Gündoğdu, E. Erzurumluoğlu, Y. Samanci, M. Vural, B. Bilgiç, H. Hanağası, B. Elibol, S. özkan (Eskişehir, Turkey)

    Objective: To report deep brain stimulation (DBS) outcomes of rare neurodegenerative movement disorders from three tertiary movement disorders centers in Turkey. Background: Deep brain stimulation…
  • 2022 International Congress

    Dystonic tremor: one symptom, different etiologies: About three cases

    S. Laroussi, S. Sakka, N. Bouattour, N. Farhat, S. Daoud, K. Moalla, H. Hadjkacem, M. Damak, C. Mhiri (Sfax, Tunisia)

    Objective: To recall some clinical situations and causes of dystonic tremor (DT). Background: DT is a tremor produced by dystonic muscle contraction. It is an…
  • 2022 International Congress

    Repetitive transcranial magnetic stimulation for hypokinetic dysarthria in PD enhances white matter integrity in the auditory-motor loop tract

    I. Rektorova, L. Brabenec, M. Kostalova, A. Sejnoha-Minsterova (Brno, Czech Republic)

    Objective: To test effects of repetitive transcranial magnetic stimulation (rTMS) for hypokinetic dysarthria in PD on white matter integrity changes of the left anterior arcuate…
  • 2022 International Congress

    Axial hypotonia – A pointer towards NBIA – PLA2G6-Associated Neurodegeneration

    VM. Mathur, DK. Khandelwal, DS. Sharma, AG. Gupta (Mumbai, India)

    Objective: While phenotypic spectrum of Neurodegeneration with brain iron accumulation is quite diverse, we discuss a case with peculiar axial hypotonia, a pointer towards PLA2G6…
  • 2022 International Congress

    Machine Learning and Instrumented Gait Analysis to Classify Subthalamic DBS States in Parkinson’s Disease

    J. Watts, A. Khojandi, R. Ramdhani (Knoxville, USA)

    Objective: This study investigates whether gait features derived from an instrumented walk can predict specific treatment conditions (stimulation frequency and medication status)  in a cohort…
  • 2022 International Congress

    A Phase 2 Randomized, Double-blind, Placebo-controlled Trial of PRAX-944 for the Treatment of Essential Tremor

    O. Olhaye, G. Belfort, S. Raines, T. Snyder, B. Ravina (Boston, USA)

    Objective: Evaluate the tolerability, safety and efficacy of PRAX-944, a selective small molecule T-type calcium channel blocker, for treatment of essential tremor (ET). Background: Essential…
  • 2022 International Congress

    Absence of nigrosome as a finding in a patient with suspected atypical parkinsonism.

    L. Caballero Sánchez, D. Cerdán Santacruz, C. Gómez López, J. Berrío Suaza, P. Gil Armada, M. álvarez Eulate, A. Castrillo Sanz, A. Mendoza Rodriguez, M. Rodríguez Sanz, C. Tabernero García (Segovia, Spain)

    Objective: Reviewing typical neuroimaging features of the substantia nigra.Noting that the absence of nigrosome 1 has also been seen in atypical parkinsonisms. Background: It is…
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