Automated quantification of facial bradykinesia through video in de-novo Parkinson’s disease
Objective: The purpose of this study was therefore to develop a fully automatic video-based hypomimia assessment tool and estimate the prevalence and characteristics of hypomimia…Clinical and genetic research in a large Ukrainian family with autosomal recessive hereditary spastic paraplegia
Objective: To perform a clinical and genetic analysis of a large Ukrainian pedigree emigrated in Italy with autosomal recessive hereditary spastic paraplegia (ARHSP). Background: HSPs…Deep Brain Stimulation for Rare Neurodegenerative Diseases: Three-Center Experience
Objective: To report deep brain stimulation (DBS) outcomes of rare neurodegenerative movement disorders from three tertiary movement disorders centers in Turkey. Background: Deep brain stimulation…Dystonic tremor: one symptom, different etiologies: About three cases
Objective: To recall some clinical situations and causes of dystonic tremor (DT). Background: DT is a tremor produced by dystonic muscle contraction. It is an…Repetitive transcranial magnetic stimulation for hypokinetic dysarthria in PD enhances white matter integrity in the auditory-motor loop tract
Objective: To test effects of repetitive transcranial magnetic stimulation (rTMS) for hypokinetic dysarthria in PD on white matter integrity changes of the left anterior arcuate…Axial hypotonia – A pointer towards NBIA – PLA2G6-Associated Neurodegeneration
Objective: While phenotypic spectrum of Neurodegeneration with brain iron accumulation is quite diverse, we discuss a case with peculiar axial hypotonia, a pointer towards PLA2G6…Machine Learning and Instrumented Gait Analysis to Classify Subthalamic DBS States in Parkinson’s Disease
Objective: This study investigates whether gait features derived from an instrumented walk can predict specific treatment conditions (stimulation frequency and medication status) in a cohort…A Phase 2 Randomized, Double-blind, Placebo-controlled Trial of PRAX-944 for the Treatment of Essential Tremor
Objective: Evaluate the tolerability, safety and efficacy of PRAX-944, a selective small molecule T-type calcium channel blocker, for treatment of essential tremor (ET). Background: Essential…Absence of nigrosome as a finding in a patient with suspected atypical parkinsonism.
Objective: Reviewing typical neuroimaging features of the substantia nigra.Noting that the absence of nigrosome 1 has also been seen in atypical parkinsonisms. Background: It is…Contribution of cognitive load to akinetic and trembling freezing of gait manifestations in patients with Parkinson’s disease
Objective: To evaluate the cognitive contribution of a dual task (DT) or motor plan updating while turning on the akinetic and trembling freezing of gait…
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