A Pilot Feasibility Study of Medium Chain Triglyceride Nutritional Ketosis and Parkinson’s Disease
Objective: To determine if nutritional ketosis supplemented by medium chain triglycerides (MCT) over the course of 2-3 weeks is acceptable and feasible in patients with…Implementing Team-Based Outpatient Palliative Care in Parkinson’s Foundation Centers of Excellence (COE): Study Design
Objective: To describe the study design and early lessons of an implementation project aiming to make integrated palliative care (PC) a new standard of care…Abnormal streamline density of the tremor network in tremor dominant Parkinson’s disease and Essential tremor plus syndrome
Objective: To evaluate streamline density (SD) of the basal ganglia-thalamocortical (BGTC) and cerebello-thalamocortical (CTC) network in tremor dominant Parkinson’s disease (TDPD) and essential tremor plus…DBS Targeting in a Neuromodulation Monitoring Unit – First 30 cases
Objective: We evaluate potential targets for Deep Brain Stimulation (DBS) based on test stimulation and chronic recording from temporary depth electrodes placed in a Neuromodulation Monitoring…A progress update on the Critical Path for Parkinson’s consortium’s pre-competitive 3DT initiative
Objective: To provide a progress update on the Critical Path for Parkinson’s (CPP) consortium’s “Digital Drug Development” (3DT) initiative, which was established in 2019 with…Prospective, Multicenter, International Registry of Deep Brain Stimulation for Essential Tremor
Objective: This is a new Essential Tremor (ET) patient registry for patients implanted with a multiple-source, constant-current DBS system capable of providing directionality for use…Short and long-term cental action of botulinum neurotoxin treatment in laryngeal dystonia
Objective: To investigate short- and long-term central effects of BoNT treatment on brain function in patients with laryngeal dystonia (LD). Background: LD is an isolated…Effect of rehabilitation interventions on freezing of gait in people with Parkinson’s disease: a systematic review and meta-analyses
Objective: To summarize the effects of rehabilitation interventions to reduce freezing of gait (FOG) in people with Parkinson’s disease (PwPD). Background: FOG is a debilitating…Chronic administration of bitopertin, a GlyT1 inhibitor, in the dyskinetic 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To evaluate if, upon chronic administration, tolerance to the anti-dyskinetic effect of the glycine transporter 1 (GlyT1) inhibitor bitopertin, would develop, in the 6-hydroxydopamine…Levodopa Pharmacokinetics in Different Levodopa Treatment Regimens plus Opicapone in Parkinson’s Disease Patients with Motor Fluctuations
Objective: This study aims to evaluate the effect of once-daily opicapone (OPC) 50 mg on the pharmacokinetics (PK) of levodopa (LD) in different LD/carbidopa (LD/CD)…
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