A mouse model to test the cortical pathogenic theory of Parkinson’s disease
Objective: To develop a mouse model of chronic corticostriatal overactivity and increase expression of corticostriatal alpha-synuclein. Background: Parkinson’s disease typically has a focal motor onset1,…Neurodegeneration and neuroinflammation for biomarker development in MSA
Objective: To investigate the diagnostic and prognostic value of fluid-based and PET imaging biomarkers related to neurodegeneration and neuroinflammation in Multiple System Atrophy (MSA). Background:…Excessive tearing; a paradoxical ocular manifestation of Parkinson’s disease
Objective: To demonstrate a case report of excessive tearing in Parkinson’s disease patient Background: Dry eye is the common ocular manifestations in PD patients. The…Alteration of peripheral blood cell profiles in Parkinson’s disease: a retrospective case-control study
Objective: The aim of this study is to investigate the relationship between peripheral blood cell profiles and Parkinson's disease (PD). Background: Abnormal immune response and systemic inflammation have…Characterization of essential tremor patients in a central hospital-based sample.
Objective: Determine characteristics of essential tremor (ET) patients in a hospital-based sample. Background: Essential tremor is the most frequent movement disorders, with an estimated prevalence…Characteristics of Fatigue and Correlation with the Symptoms of Parkinson’s Disease
Objective: We aims to assess the frequency and severity of fatigue, to explore the clinical features and associated factors of fatigue, as well as to…Pronunciation characteristics of patients with Parkinson’s disease based on sustained vowel speech
Objective: This study attempted to objectively analyze the acoustic characteristics of PD by using dynamic laryngoscope DIVAS2.5 acoustic analysis system and Praat acoustic software, and provide…A role of β2-adrenoreceptor agonist related to the development of Parkinson’s disease
Objective: To explore β2AR agonist’s effect on PD development with controlling for smoking. Background: Several studies have suggested the potential protective role of β2-adrenoreceptor agonist (β2AR…Improvement of masticatory muscles’ pain versus tenderness via electromyography biofeedback training in patients with bruxism.
Objective: To determine if masticatory muscles’ pain and tenderness in bruxers should be treated independently. Background: Bruxism is a movement disorder with marked hyperactivity in the…Depression and progression of motor symptoms in early stage of Parkinson’s disease
Objective: To investigate the association of depression with the progression of motor symptoms in patients with early-stage PD. Background: Depression is a major nonmotor symptom…
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