DBS for a patient with KMT2B-SHANK2 related dystonia
Objective: Describe a case of deep brain stimulation (DBS) outcome for a patient with pathogenic variants of Shank2 and KMT2B genes. Background: Prior reports have…Brain glia activation and peripheral inflammation in Parkinson’s disease: a PET study
Objective: Abnormal activation of immune system is an important pathogenesis of Parkinson's disease, but the relationship between peripheral inflammation, central glia activation and dopaminergic degeneration…Telemedicine in speech and swallowing disorders for patients with Parkinson’s disease: Motivation and satisfaction of patients and speech language pathologists
Objective: To assess the satisfaction with telemedicine for speech and swallowing disorders among patients with PD and speech language pathologists (SLP) as well as the…The mitochondrial risk score and lifestyle factors are associated with age at onset in LRRK2 p.Gly2019Ser Parkinson’s disease.
Objective: To investigate the relationship between a mitochondrial risk score (MRS), lifestyle and age at onset (AAO) in LRRK2 G2019S Parkinson’s disease (PD). Background: PD…A novel platform for home-based, remotely supervised, transcranial direct current stimulation treatment and assessment for Cerebellar ataxia: A randomized, double-blind, sham-controlled, crossover, feasibility study
Objective: To evaluate the feasibility of home-based transcranial direct current stimulation (tDCS) for people with cerebellar ataxia (CA). Background: tDCS induces non-invasive cortical plasticity via…Exploring the diversity of alleviating manoeuvres in Cervical Dystonia
Objective: We explored five different categories of alleviating manoeuvres (AMs) in patients with cervical dystonia (CD): pure sensory; sensorimotor manoeuvres in which sensory input is…Differences in cognition and neuropsychiatric profiles between asymptomatic and symptomatic carriers of Huntington’s disease
Objective: To analyze cognitive and neuropsychiatric differences between asymptomatic and symptomatic carriers of Huntington's disease (HD) compared with healthy controls (HC) taking into account the…Parkinson’s Disease, Cognition, Positive Symptoms and Medication Management
Objective: Explore the relationship between multi-domain cognitive testing and patient-reported psychiatric symptoms in PwPD to self-medication management capabilities. Background: Parkinson’s disease (PD) is a complex…Cerebro-cerebellar motor networks in clinical subtypes of Parkinson’s disease
Objective: This study investigated functional alterations within the cerebro-cerebellar system in tremor-dominant (TD) and postural-instability-and-gait-disorder (PIGD) subtypes of Parkinson’s disease (PD) using stepwise functional connectivity…Reduced Risk of Mortality and Antipsychotics in Parkinson’s Disease-Related Psychosis: Pimavanserin vs Off-Label Antipsychotics
Objective: Summarize the available data for the mortality risk associated with Parkinson’s disease (PD) psychosis (PDP) and pimavanserin. Background: PDP is associated with increased mortality…
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