Diverse alteration of brain networking in PD with ICD-RBs
Objective: To investigate possible brain network indicators in Parkinson’s disease (PD) with impulse control disorder and related behaviours (ICD-RBs) using resting state functional MRI (rs-fMRI)…The impact of thyroid disease on severity of motor symptoms in Croatian residents with de novo Parkinson’s disease
Objective: The goal of this study was to investigate the association between thyroid disease and severity of motor symptoms in Croatian residents with de novo…Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study of Ecopipam in Children and Adolescents with Tourette Syndrome
Objective: Evaluate the efficacy and safety of ecopipam in children and adolescents with Tourette’s Syndrome (TS). Background: Ecopipam, a first-in-class selective dopamine-1 (D1) receptor antagonist…Development and validation of clinical scales for defining RBD severity in participants of the North American Prodromal Synucleinopathy (NAPS) consortium
Objective: The objective of this study is to assess the internal validity of the REM Sleep Behavior Disorder (RBD) symptom severity scale (RBDSSS) and its…Blood biomarkers and their association with non-motor symptoms in early Parkinson’s Disease
Objective: To identify if baseline blood biomarkers are associated with non-motor symptoms in early PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with…Bilateral Magnetic Resonance Imaging-Guided Focused Ultrasound Thalamotomy in Medication-Resistant Essential Tremor Treatment.
Objective: To assess the efficacy and safety of bilateral magnetic resonance imaging-guided focused ultrasound thalamothomy for medication refractory essential tremor in prospective observation of two…Classical Machine Learning approaches to automate tremor detection from electrophysiological data
Objective: To detect tremor syndromes from electrophysiological signatures using classical machine learning techniques. Background: Electromyographic recordings combined with accelerometry data are widely used to measure…Diffusion-weighted imaging based free-water investigation in Parkinsonian disorders
Objective: To investigate free-water (FW) changes in Parkinson's disease (PD), Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Background: Various parkinsonian syndrome includes PD,…Unilateral Hypertrophic Olivary Degeneration in Anti-GAD-associated Encephalomyelitis
Objective: We present a patient with GAD65-Ab-related encephalomyelitis who developed unilateral hypertrophic olivary degeneration (HOD) in the absence of structural lesions within the Guillain-Mollaret triangle.…Computer vision can detect changes in bradykinesia associated with dopaminergic state in Parkinson’s disease
Objective: To evaluate the classification accuracy of a computer vision-based feature extraction and classifier method to detect changes in finger tap bradykinesia associated with dopaminergic…
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