A double-blind randomized clinical trial to evaluate the effects of Candesartan for Cognitive and Neuropsychiatric Impairment in Parkinson’s Disease
Objective: To explore the feasibility of repurposing candesartan for the treatment of cognitive impairment and neuropsychiatric symptoms in PD. Background: There is an urgent need…Sigma Absolute Spectral Power is Associated with Depression in Parkinson’s Disease
Objective: This cross-sectional study investigated the relationship between depression and sigma absolute spectral power (9-15 Hz) in the frequency range of sleep spindles during non-rapid…Association Between Over-the-Counter Dietary Supplements and Parkinson’s Disease Symptom Severity Over Time
Objective: The goal of this study was to evaluate whether the use of nutraceuticals and dietary supplements are associated, on a population level, with Parkinson’s…Gene and variant curation of Parkinson’s disease genes by an authoritative expert panel
Objective: Establish an authoritative central curation for causative genes and variants for Parkinson’s disease (PD) Background: The urgency to establish central curation for causative genes…Patient Advisory Boards: A Model for Patient Engagement in Parkinson’s Disease Comparative Effectiveness Research
Objective: To build a replicable, sustainable model of patient engagement in Parkinson’s disease (PD) comparative effectiveness research (CER) at academic research centers through patient advisory…Prediction of early-stage Parkinson’s disease using connectivity and morphometry of the striatum
Objective: To parcellate the striatum into sub-regions and extract connectivity and surface morphometry features that can distinguish early patients with PD using machine learning. Background:…Deleterious GRN mutations: a new player in the etiology of Lewy body dementia
Objective: In this study we investigated the association of GRN damaging mutations in the etiology of Lewy body dementia. Background: Lewy body dementia (LBD) is…A 69-year-old man with seizure-like activity and unresponsiveness
Objective: Highlight the clinical features and radiologic findings of diabetic striatopathy. Background: Diabetic striatopathy is a rare condition associated with chorea and/or ballism but can…Are Subjective Cognitive Complaints a predictor of future cognitive decline in Parkinson´s Disease? – A longitudinal study
Objective: We aim to determine whether subjective cognitive complaints (SCC) may predict the development of cognitive impairment in Parkinson´s Disease (PD) Background: Subjective cognitive complaints…Monogenic Hub of the Global Parkinson’s Genetics Program (GP2): In search of new PD genes
Objective: To identify novel monogenic causes of Parkinson’s disease (PD) by performing short and long-read sequencing for up to 10,000 PD patients and families with…
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